The preference shift toward high-protein, lower-reward foods is the GLP-1 receptor mechanism working on palatability circuits beyond appetite suppression - the 'gross' response to formerly rewarding foods follows the same pathway as food noise reduction.
The facial volume change is proportional to fat loss rate and baseline adiposity, not medication-specific - any rapid weight loss method produces the same effect.
Just be mindful of potential side effects as you increase your dosage. Some people experience restless legs at higher doses. If that happens, talk to your doctor about possible solutions.
Keep it in the fridge and keep using it. At the very least, it might lose some of its effectiveness, but I would absolutely use it. They're so expensive!
I agree with Veggie-Coffee about minimizing meal sizes. Portion control is key on this med. It's not about deprivation, it's about eating mindfully and stopping when you're satisfied, not stuffed. A smaller plate can really help with that.
If the concentration remains the same, doubling the units is equivalent to doubling the dose. That can hit you hard. While there's a standard titration schedule, those large increases can be tough. I advise listening to your body and perhaps taking a slightly smaller increase the first week if...
I agree with PulseBTW445. The mirror can be deceiving. I've found that photographs really highlight the difference. You also might notice inflammation reducing as you lose weight.