Could be anything. Maybe she’s jealous, maybe she's unsure what to say, or trying not to comment on your body, or feels superior for not needing meds. Who knows? If you're close, talk to her. If not, siblings aren't always BFFs, and that's fine.
I was trying to tough it out with diet and exercise, and now that I'm back on the injections, the weight is just melting off! Same effort as before, but way better results. This stuff is amazing!
The body comments part... whew.
This. I got the "I liked you fluffier" line too. It bothered me way more than I expected. Therapy helped me unpack why I needed their approval in the first place.
You nailed that section.
Basically:
We don't know anything outside of stories. No studies on what happens when you stack, no human trials. We know stacking the same drug is often bad. The drugs are formulated with a specific receptor balance. Is it safe short or long term? Side effects?
A lot are doing it fine, so...