Weight loss weirdness...

Scale stalls after a drop are almost always water and body adjustment, not the medication losing effect. Clothes fitting or measurements might still be changing even when the scale isn't moving. Usually breaks through in a week or two.
 
The 35-lb loss from 285 with the feeling-off experience is worth tracking - at that scale, body composition shifts can create a disconnect between the mirror and expectations, especially when torso fat changes before facial appearance catches up. Scale calibration matters here: home versus medical office scales vary by hydration timing, clothing, and time of day. Pre-appointment weigh-ins are the more controlled comparison, but neither reading is wrong.
 
Metformin plus MJ has supporting data. The insulin sensitization effect adds something beyond what tirz does alone.
 
Rapid loss creates real systemic effects. On bone density the window that matters is now - resistance training during loss does more than starting after.
 
The disconnect between what the scale says and what you actually feel is real and well-documented - body image tends to lag behind physical change, sometimes by months. The 'off' feeling is a common phase, not a sign something isn't working.
 
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