BPC/TB Blend or Separate?

For joint vs gut the split matters - TB-500 handles most joint work, so separates give more control. BPC alone covers the gut side well with less injection frequency than blend protocols require.

The local versus systemic delivery distinction is worth keeping in mind - BPC's mechanism for acute injury benefits from proximity to the target tissue, while TB-500's systemic action doesn't require site targeting. A blend means you're not optimizing for either mechanism simultaneously.

The local injection debate for injury-targeted peptides is genuinely unresolved in the evidence - BPC-157 and TB-500 are systemically acting compounds rather than purely local ones, which suggests the injection site may matter less than generally assumed. The case for proximal injection is that local tissue concentration may be higher in the target area, but the compound reaches the target site systemically regardless. Running a proximal-then-systemic comparison in sequence would answer the question for your specific response better than either theory

The BPC and TB together vs separate question tends to come down to whether you want flexibility to dose each independently. Running them separately means you can adjust one without changing the other if something isn't working. GLOW/KLOW as a pre-blended option does simplify it but you lose that individual control.