NAD+ messing with my blood sugar?

NAD+ affecting blood sugar on tirzepatide with a CGM is worth monitoring - any supplement with insulin-sensitizing properties shifts the baseline the medication is calibrated against. Berberine is the most documented case. NAD+ precursors affect glucose metabolism through mitochondrial pathways - the CGM should show the pattern within a few weeks.

The caffeine angle is worth checking first - GLP-1s often reduce intake naturally, and withdrawal shows as cortisol-driven glucose variability on a CGM even without obvious symptoms.

Nighttime blood sugar dipping on tirzepatide is more common than people realize - the appetite suppression carries into overnight and caloric intake drops below what the med expects. The banana or small carb snack strategy works because it gives glucose without triggering full digestion load. With NAD+ in the mix now, worth ruling out the baseline tirz behavior first before attributing spikes to the supplement.