Anyone else use THC? I've found that even though my appetite is reduced overall, if I use cannabis, the munchies can overpower the medication. I try to use it later in the evening so I can just go to sleep before the munchies kick in!
The direct intervention preference over just managing symptoms is the right frame for the senolytic discussion. The mouse study data is compelling at the mechanism level and the extrapolation to human outcomes is where the uncertainty sits. Getting at the underlying cellular senescence rather than compensating for it is the longer-term goal. Are you tracking anything specifically to test the hypothesis?