GLP-1 shot and vacay?

So you've got a full week before the trip starts? Different story if you were leaving sooner, but if the lowest dose gives you rough side effects from one shot, they should be completely gone well before departure.

If that ends up being the case, just push dose number two back by several days and save it for near the end of the trip instead. And if you end up having no real side effects, just stick with the original plan.

Was traveling for a few weeks straight. Injected the evening before departure, since shifting the timing a few days either direction from your usual schedule is fine, injected again mid-trip since storage temperature stops mattering once a pen's already in use, then once more after getting home. Lucky enough to have a single-dose pen on hand for that stretch. Wouldn't recommend skipping a full two weeks though.