Mounjaro for T2D but weight loss stalled?

Hong Kong Yanpep International
no sides yet? slowly titrating up should be okay but watch your blood sugar and keep electrolytes up. smartest move is hold 2mg for a couple more weeks, then 4mg if needed. don't pin every 3 days or add variables this early.
 
new to this, week 2 on mounjaro. started cause my blood levels were out of whack, not really chasing weight loss. curious to see how losing weight will show off my muscles though. what's all the HW/SW/CW/GW stuff? and how do you know when to bump up from where you are?
 
The reversal picture for T2D on Mounjaro is different - the glycemic management piece needs a bridge, not just an acknowledgment that hunger returns. Discontinuation without a transition plan is the risk that gets underweighted. For T2D the primary effect is metabolic correction; the hunger piece is secondary.
 
The glasses analogy is the right frame - corrective intervention for a metabolic condition doesn't have a natural exit if the underlying condition persists. For T2D specifically, the A1c and insulin resistance data makes the case for long-term use independently of the weight loss benefit. The dose reduction protocol - finding the maintenance dose rather than stopping - is the evidence-based approach when the concern is dependency rather than medical necessity.
 
The willpower framing has been wrong for decades and the GLP-1 evidence base makes it definitively wrong now. Obesity has physiological drivers that no level of discipline addresses directly. The people who failed repeatedly weren't character flawed - their biology just worked against them.
 
the willpower argument really does fall apart when you look at how these medications work. metabolic dysfunction is not something you can out-motivate yourself through and it is good to see more people understanding that. there are active communities specifically for people in maintenance and stall management that are worth finding.
 
The published statistics on what happens when people stop because they think they've achieved a weight loss goal rather than recognizing it as metabolic management are stark. Stalled weight on Mounjaro for T2D isn't a failure of the medication - it's the body finding a new homeostasis that the medication has to actively maintain. What's happening on the A1C side while the weight is stalled?
 
My doctor's fully on board with intermittent fasting and structured therapeutic fasts, and has me on Mounjaro for my T2D. Zero pushback from her about combining fasting with the medication.

Hoping to connect with others doing the same combination.
 
Good news is my doctor actively supports intermittent and therapeutic fasting alongside my Mounjaro prescription for T2D. She hasn't raised a single concern about running both together.

Would love to hear from anyone else pairing these two approaches.
 
Found out last month that I have T2DM, and my doctor started me on Mounjaro to bring my A1c down, the thinking being that losing weight should help with that too.
 
Started Mounjaro originally to manage T2 diabetes, diagnosed twelve years back and built up solid habits early on.

Then menopause hit and threw everything into chaos, no matter how little was eaten or how much exercise happened, even with metformin dosage pushed higher, the numbers kept climbing on both fronts.

Now that Mounjaro's part of the routine, those older good habits are working again. Weight loss isn't really the focus, but it's happening anyway. A tank top gifted a while back never fit right until recently, and now it sits comfortably instead of feeling too tight.

Still pay close attention to nutrition labels to make informed choices, since this doesn't cure the underlying condition, but calorie or macro counting isn't part of the daily routine. An occasional spot check is fine, just not something sustainable every single day.

What's appealing here is how much less mental energy food takes up now. Traditional dieting tends to make food consume every thought, but now there's room to just focus on people and things that matter more.
 
Insulin resistance, weak appetite suppression and metabolic issues can all play a part, but focusing on them may overcomplicate things. On paper weight loss is very simple, even if it's hard in practice. Your body needs a set number of calories, set mainly by how heavy you are and your make-up, with metabolism playing a small role, so to lose you must eat less than your maintenance level. Mounjaro is no miracle. It doesn't change how your body handles calories, it mainly makes you feel fuller and less hungry, acting like a pill version of a gastric band. Result: fewer calories eaten, weight lost. For most people it does that easily and naturally, but you could be a non-responder. Even with insulin resistance or extra belly fat, eating below maintenance means you will lose.
 
Mounjaro is mostly prescribed for T2D, unless you got an exception. I'm T2D and dont plan to taper off, since my A1C used to hit 13 and Mounjaro brought it to 6. I'm at the stage of stepping down, seven and a half to five, for extra energy and less constipation, though I intend to stay on 5mg for life. Tirz is what my spouse uses, aimed at weight. She was pre-diabetic without having it, and needed 6 months to reach 2.5mg. We worked hard to cut bad foods first: soda, white bread, bagels, chips and processed meats all went, since they offer close to zero nutrition. After about two rough months we landed a great maintenance plan. Lifting is a must on this med, even just free weights and free YouTube videos.
 
HeartCoffee Thanks for the kind words. My endocrinologist is amazing, and yes T2 was the first order of business. Tests ruled out thyroid, cortisol and so on, and I have MASH. Mounjaro helps me metabolically but not with weight loss. I'll ask my doctor about switching to Ozempic, since the GIP in Mounjaro may not suit me. I'd hoped Retatrutide would arrive, but it's in its last trial stage and not available until 2028.
 
Sounds like classic reactive hypoglycemia. T2D livers run unregulated, pumping glucose nonstop, bouncing you from high readings to even higher ones. Mounjaro clears liver fat, making the body more insulin sensitive. Eat fast carbs, pancreas dumps insulin, sensitive body pulls that sugar out fast. Systems like glucagon, cortisol, adrenaline normally kick glucose back up, and GLP-1 dampens glucagon some but still functions when you go low. Went through this adjusting myself. Exercise complicates it further. Had to cut carbs to stop it, so try lower carb and skip fast carbs a while, body should adapt. The crash can make you crave an entire dessert, so I kept glucose chews in my gym bag since it only hit after carbs plus training. Four grams, a single tablet, usually settled things again.
 
For those of us dealing with T2D, Mounjaro tends to fix the underlying metabolic stuff first. The real target is A1C, not the scale. Dropping pounds is just a bonus that comes along with getting that balance right, a nice bonus, but still just a bonus. Honestly thats a good thing.
 
You must log in or register to reply here.
Back
Top