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The combination of elevated cholesterol, pre-diabetes risk, and limited mobility all improving together is the full case for long-term medication - the quality of life change makes the argument itself.

IM in the ventral glutes is where a lot of people land after working through the site options - the consistency tends to be better than subq for some compounds, and the every-other-day cadence holds up well once you're past the early adjustment.

Down a size in a few months and still moving - the clothes fitting differently tends to land harder than the number on the scale. Happy in both photos is the real before/after.

Umm, what does that even mean, dude? Just kidding, friend...

I located this article, maybe its helpful...

If anyone ever figures this out, please share! I've been researching this for what feels like forever and I can't seem to understand it because the standards are measured in absorbed endotoxins per kg of body weight per hour. We need a thread dedicated to understanding endotoxins for sub...

You might dig this: healthrising.org article on GLP and fatigue. I had gastro stuff at 0.25mg but famotidine helps. Trialing glutathione, glycine, NAC so I metabolize thiamine better.

That is so inspiring! I started a month ago, currently down 15lbs. Gives me hope for the future!

Amazing, congratulations!

Incredible achievement! What dosage are you currently taking?

I'm so inspired by seeing everyone's progress! I'm a slow loser, but I'm trying to stay positive. It's hard when you see people losing like crazy fast. Thanks for the reminder that

I started feeling the effects almost immediately. Maybe I shouldn't increase the dose as quickly as they say?

You look great!!!! Congratulations 🙌

You should try splitting the dose. Inject half on day one and the other half on day four. It helps a lot of people because it spreads the dosage out. You could also up your dose a bit. Try doing .65 on day one and .65 on day four.

How are people losing so much weight in just 20 weeks? Like, forty pounds in five months? I only dropped about 30 in a year. If your dose is higher than mine, you must be throwing up all the time due to reflux and nausea. I'm already nauseous a few times a week on a lower dose. How are the side...

I split my dose into two injections per week, Tuesdays and Fridays. I also inject into my upper thigh. I find that helps a lot with the nausea. My main focus is keeping my blood sugar stable, not so much weight loss, so your results might vary. I've also heard that changing where you inject can...

I've been on Ozempic for like, six or seven years now. I have type 2 diabetes and PCOS. The first couple of years, I didn't see too much change on the scale, though my numbers were better. I couldn't get below 220. I was exercising and doing what I was supposed to. Then some stressful stuff...

I just feel beyond blessed this medication exists. Finally, I don’t have to constantly think about food all day. It’s so freeing!

It takes over a month for Ozempic to build up in your system… Everyone reacts differently. I’ve been on 0.25 since summer '24 and I haven't needed to increase my dose. Started at 215, now I'm 152

In the same boat and trying to lose again. I won't sugarcoat it; it's hard and depressing. Sorry for not being more helpful. I'm dealing with a depressive episode because of this (mentally exhausted from losing the weight again) and just trying to share the reality.