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The transition window from tirz to reta is where most people underestimate the starting dose - going in too low means several weeks before any signal on weight while the system adjusts.

Most people notice it somewhere between week 2 and week 6 at the starting dose - it varies more by dose and individual response than by timeline.

The question is what stopping actually costs. For most people the weight comes back. The medication was designed for long-term use, not as a short-term fix.

It improves! I was in the same boat. The first week was the worst. Slowly reintroduce foods in small amounts during weeks 2 and 3. By week 4, you should be able to eat more normally (except for greasy, fried, or very fatty/sugary foods. Those still don't sit well with me and probably never will...

Thanks for sharing on the community! Just a quick reminder of the rules. We don't allow discussions about non-FDA approved semaglutide versions, or selling/offering meds for sale, even in DMs. Don't ask for or accept DMs from anyone who is offering meds, they aren't endorsed here. If you're a...

Anyone have advice on spacing out doses for maintenance? I've dropped around 95lbs since January. Switching to paying out of pocket so trying to make it last.

If you're open about having diabetes, why feel embarrassed about taking medication for it?

What kind of exercise are you doing to get those muscles?! You look so strong - that's how I want to look!

That's great that you've begun! You don't have to tell anyone. It really isn't their concern, and some people simply don't want to know every detail. Do people announce they need new glasses? It's similar. Keep it private.

Yeah, same here, barely sleeping since starting sema. Is it worth it?

I'm starting to collect my used injection pens. What does everyone do with them? I'm worried about the needles.

That's Wonderful!! :)

I've also heard that sometimes those cravings are worse right before your period? Maybe that's a factor, FastingIMO286?

That's fantastic!!!! I'm currently down to 295 from a starting weight of 333. It's a gradual process, but your journey is giving me hope. Keep up the amazing work. I'm hoping to be where you are around my one-year mark next winter, or even sooner.

Thanks, everyone! It's really validating to hear that others are experiencing similar things.

Hey everyone, I had a little win I wanted to share because it feels HUGE. I've got PCOS, and I've realized my insane appetite is probably linked. I've always eaten EVERYTHING. Carby stuff especially sets me off, and I just can't stop once I start. I could never get the scale to budge, and...

That's a huge change! It really suits you!

Try taking powdered magnesium citrate (like the CALM brand) before bed. Mix 1 tablespoon into water, and things should get moving the next day. Magnesium citrate draws water into the colon, plus you get a dose of magnesium to help you sleep. It's a win-win and better than chemical-based solutions.

Wow, that's incredible! I'm just starting out. What was the hardest part for you?

I'm in a similar boat. Four weeks at 0.25 and two weeks at 0.50. I'm dealing with constipation and taking Metamucil. I'm down 18 pounds. You look great; keep up the good work!