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I've experimented with this. You can either increase the amount you inject each week or inject the same amount more often (like every 6 days). I use a calculator that projects how much Tirz is in my system to adjust dosage/schedule very precisely. Makes sense to use the smallest dose needed to...

I'm about 5'1" and went from 186 to 130. Been on 7.5 mg for about five months. My clothes were just hanging off me one day. Some I had been holding onto for YEARS. A wild ride!

Awesome work!!!

I've been on a similar road myself. 5' 7", went from 220 down to 130 this past year using sema.

That's amazing, Wes_19! You're inspiring me too! I've been on a similar path, using semaglutide, and it's incredible to see what's possible. I've dropped about 40 pounds since February and finally hit a 'normal' BMI too!

Have all the fun Wes_19!! 🎉🎉🎉🎉

That's awesome, Wes_19! Congratulations!

As someone with insulin resistance and PCOS, I'm watching the small-molecule drugs closely. If orforglipron truly avoids the strict absorption window, that could be huge for adherence. Daily morning rigidity is tough when you already juggle metformin, supplements, and sometimes fertility meds...

I saw someone on Reddit mention they started getting heartburn and nausea on 0.5mg. They decided to stay at that dose for a bit to see if it calms down before increasing it. Maybe that's an option?

This article has some great info: another forum

Incredible! Great progress! Congrats on your journey.

Way to goooooooooooo! 🎉🎉🎉