I wonder if they'll do the same thing with reta later? The max dose is 12mg/week now. Maybe they'll go up to 16mg? Reta is stronger than tirz, IMO. Sema is stronger than both. I couldn't handle 1.5mg of sema without bad side effects. 0.8-1mg is my max. I could do 5, 7.5, 10, even 12.5 of tirz...