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Reta plus tirz is a reasonable stack. Adding MT2, NAD, GHK-Cu, and cagri simultaneously is a different level of variable - if something goes sideways you won't know which compound caused it. Adding one at a time with a few weeks of baseline between each is the standard way to keep the feedback...

Protein first at every meal - hunger cues shift fast and protein protects muscle.

Ice before and after injection is legitimately effective for site discomfort - the cold numbs the nerve endings and reduces bruising. The placement note about staying above the belly button is also real; lower placement tends to hit more sensitive tissue.

Awesome! Are you dealing with loose skin?

Congrats!!

That's such a huge difference! You must feel so much better, too.

I'm about 6 months in on sema. It's been a bit slower than I hoped (only about 30lbs down), but consistent. I had a stall last month and had to up my dose a little.

You did great!

Great work. Really impressive Keep going

That's what I like to hear. Managing side effects is key and it sounds like you're finding what works for you.

Imagine driving a car at a certain speed, but only being able to read the tachometer (RPMs) and not the speedometer. You'd eventually figure it out, but you'd get confused on hills and wonder why your system gives weird results. That's what it's like trying to understand symptoms/levels of a...

It's off and on. It's normal some days, and clearly reduced on others. The biggest side effect I'm feeling is that my stomach gets full much faster, but the bloated feeling has been less lately. I think it will come back with the higher dose. My doctor said this is just a starting dose and won't...

Well, it's been a month and I've lost about 5 pounds. I'm starting the next dose, .50mg, on Thursday. I have a telehealth appointment today before they increase my dose. I hope I don't have to do this every month for the next dose. My side effects are gone now. Funny, they initially said the...

It's interesting... after 3 days, I have nausea and less appetite. I've lost 2 pounds, which is probably water weight. Is it just a placebo? I don't know, but the compounded semaglutide I took for a month did nothing. Maybe it was a bad batch? Either way, that's 2 pounds more than I've lost in...

I understand. I've been working on this for YEARS, so my goal is to get back to a healthy weight, stop the meds, and fight to keep the weight off. I already have a fitness routine. My problem was "bulking" up, which I did... lol, now losing the fat is the issue. I hope this will give me a boost...

Yep, the doctor mentioned protein too. I don't want to lose the muscle I worked hard for. I'll check out the other stuff. My wife started this a while back and deals with constipation, so I'll look into psyllium. Thanks!

I had a checkup recently. My doc was happy with my blood work and everything, but said I'm too heavy. They know I have muscle, but think I should lose some fat (I'm 5'11" and weigh around 225). I told them it's been harder as I've gotten older (I'm 60). It used to be easier to lose weight! I...

I understand how you feel. I am on it for T2D. I started around 185lbs back in May of 2024, and I'm now down to 120lbs. I also had breast cancer last year, so between the saggy skin and the butt that looks deflated, I also have scarred breasts. I enjoy the lower A1c and surviving cancer, for...

I get it. The skin thing sucks, big time. It's too bad there aren't better resources for folks to get skin removal without going broke, because it'd do wonders for mental health. I've hated taking my shirt off in public forever. It's easy for people to say it's all mental, but it's a lot harder...

I've read that you get the best results with intra-nasal administration. I think that's how I'll try it when mine arrives.