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Six weeks at 4mg weekly equivalent after 12.5mg tirz means your receptor sensitivity is effectively being rebuilt - the Reta onset after a tirz transition often feels slower than starting fresh because of receptor downregulation. The 2mg every 3 days pattern is the right setup for escalating...

Lipase elevation is worth flagging because it can precede pancreatitis even when symptoms are absent. GLP-1s generally improve triglycerides along with other metabolic markers, which is the typical pattern. The lipase piece warrants a direct conversation with your prescriber.

Gym confidence after insecurity that deep is the win the scale never shows.

Went shopping today and realized summer clothes from last year don't fit—I've dropped about 25 kg. Clerk suggested an M, I knew better and grabbed an L. She ended up hunting down all the M sizes. Never worn an M before. 9 months in at 5 mg, food noise creeping back but slow. Might up the dose...

Try calling local pharmacies or hospitals that work with Pfizer reps. They can order it, especially if it's for research purposes. A hospital connection is gold - my doctor helped me get bulk orders so I'm set on BAC water for ages.

never push peptides on anyone directly. people hear about the 7kg of chinese tirz in my freezer though and think it's hilarious. every now and then someone slides in asking about the mystery powders. i answer questions, and sometimes they end up curious enough to try their own.

Ugh, I can't stand these ranting posts. They're so annoying.

Yep. Been on semaglutide since last summer and started creatine at the same time. My weight loss isn’t super quick, but my body fat % is dropping faster, and I’m lifting more than ever. It’s been a great addition to semaglutide for me!

Has anyone started creatine supplements to help with gym workouts while taking semaglutide? What has your experience been? I just started about a month ago, and I feel better during my workouts. Curious if anyone else has tried this combo!

The main issue is if you don't establish healthy habits, you'll likely bounce back when you stop. Going through weight loss and gain cycles might do damage to your body composition in the long run and cause unforeseen health issues.

The reset of the dopamine/reward system? That's the best part! Worth it for that alone.

Thanks! Definitely feeling healthier. Less inflammation, more energy. It's been pretty amazing.

I started at the lowest dose, I think like 2.5mg maybe? I lost around 7 pounds the first couple weeks, it wasn't dramatic early on.

Thanks guys!

I started near 260 in late autumn last year and today the scale said 142. That's over 110 pounds GONE. I still can't believe it. I want to lose another 10-15, but now I'm all about building muscle. My goals are SO different than when I started!

If someone can't handle a fart, they ain't the one! 😂

Great job!!! I'm just about to begin.

Keep it up!!

I went from a size 22 to an 8 in roughly 3 years. I still don't recognize myself in the mirror sometimes.

You're a good looking dude, don't sweat it! You're doing great! ❤️🙏