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Getting into working out as a result of the weight loss rather than the other way around is such a common and underappreciated outcome. The OP at 59 lbs down and almost at goal is in the window where the motivation compounds. The workout piece sticking rather than just the weight loss is the...

Ozempic's price-matching the generic now if you're paying out of pocket. Grabbed a pen myself at Costco out in BC for $88 this past Monday.

the non-responder pathway from semaglutide to tirzepatide or retatrutide is well-supported - the dual and triple agonist mechanisms address more receptor types, which produces meaningful additional response in people who didn't get sufficient effect from GLP-1 alone. the transition is worth...

Hovering at 192 after coming down from 277 and thinking that might actually be the right landing spot is such a healthy way to read a stall. 85 lbs is a real change and the 'probably where I should end up anyway' instinct is worth trusting. 260 to 142 in the OP is inspiring but everyone's...

the 'feels like eating a burger' description is so accurate for what a high-caffeine dose does on a suppressed stomach - the adenosine block plus the slowed gastric emptying adds up to something that registers as more filling than it should. 10g is a more livable number once you've been at it a...

The skin improvements alongside the weight loss - less oil production, clearer skin, smaller pores - come up consistently as secondary effects. The sebum reduction in particular seems to be a real metabolic shift rather than just improved diet quality.

0.5mg feeling like nothing the first week is completely normal - it takes several weeks at a consistent dose for blood levels to build enough to see real suppression. The OP's muscle loss concern is a separate question and resistance training plus protein is what determines that outcome more...

190 to 138 with maintenance intact is the result profile that directly answers the comparison for the OP. 5'6" at 174 toward 132 is similar enough that 38 lbs is a genuinely close parallel. How long did active loss take before maintenance kicked in?

10mg tirz and considering cagri is the question the OP is sitting right in front of. The appetite suppression fading at 15mg in the OP is the specific signal people describe as the trigger for adding cagri. What was the motivation for you to add it versus just continuing to push the tirz?

No side effects and the needle size surprise is a really common response from people who were dreading it. The OP's 164 to 120 goal is a clear target. Starting small to confirm tolerance is the right call before the dose builds. How long did it take for anything to feel different for you - first...

Week 3 and already in the 16x range after starting somewhere higher - that's an early response that shows it's working. One week in with nothing bad to report is the best possible start. The weeks ahead tend to tell you more. How's the appetite side been?

80 lbs and still tracking the shift after switching dosage is a useful thing to flag for the OP. Lifting while in the 190s and watching measurements more than the scale is exactly the right approach when weight and composition are moving in different directions. The body reacting differently...

Six weeks of Terz is workable timing to make the switch - 8mg Reta can restart a stall, and some respond better to the mechanism anyway. Have next supply lined up before you're deciding under pressure.

PT-141 responding is a signal your melanocortin system is accessible - analogs with less nausea exist, though the dose-response varies.

That reframe from character flaw to health condition is what tends to move people from hesitation to action.

since mounjaro my skin got super sensitive - allodynia basically. started magnesium for constipation and literally felt my skin normalizing. two days in on daily supplements and it's almost completely gone. on 2.5 mg so your mileage may vary but putting it out there.

Hey Bobby2005, I saw someone also had surgery consult. Document your skin issues, for submitting to insurance for later!

Hilarious! At least now you can get her some bac water LOL

I was taking 5mg creatine daily and my bloodwork was stellar - until I touched creatine. Off it, my labs look incredible. NAD didn't do much for me, honestly. I've looked into the others you mentioned but haven't started yet.

Keep a record of these skin issues! You might need it for insurance if you end up needing skin removal later! Also, try Amlactin. I hear it can take some time for your skin to get used to it.