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just grabbed a -20C lab freezer for under 100 bucks. has alarms and stuff. wondering if it's actually worth it vs a regular fridge for long-term storage, or is it just nice to have?

Lilly's still running clinical trials on higher doses without canceling for safety, and we've both done higher doses, so 15mg definitely isn't the ceiling. Thought about going to 25mg but not sure if that's the move.

reading more about glps and what it takes to keep weight off and yeah obesity's a condition, some of us got it. medicines help but temporary — real fix is lifestyle. only like 4-6% of people keep it off long-term and you know what that takes? tapering off, moving, clean food, sometimes fasting...

Absolutely. Cortisol spikes from stress interfere with the med's effectiveness. Look into ashwagandha for cortisol management. Magnesium glycinate before bed might help too, especially if stress affects your sleep.

congrats on the work. if 15mg works better for maintaining, maybe stay there? staying on it has health perks outside of just weight loss.

I don’t say force it. I *choose* to eat a tiny, healthy portion. A handful of thawed shrimp with cocktail sauce. Pepper slices with hummus.

Not enough protein = hair loss.

There's a lot of emerging research that GLP-1 agonists don't just affect appetite, but also have a major impact on emotional regulation and mental health. Some studies are showing a connection between stress/PTSD and overeating, due to the endocrine system and stress hormones.

To those asking about where to get semaglutide: remember we can't talk about specific sources here. Consult your doctor for safe and legal options.

It's also possible the medication itself isn't great. I switched pharmacies recently and the stuff I'm getting now is basically useless. I'm on a high dose and can barely tell I took anything. I'm looking for a different provider and pharmacy ASAP.

Congratulations!

I'm not even 72 hours after the first dose and I feel I'm back to normal. It's still early and it hasn't built up in my system, and 2.5 isn't therapeutic, but I secretly hoped I wouldn't have to really struggle after the first 48 hours seemed so promising!

This totally happened to me when I was on Ozempic. Every time I went up a dose, the food cravings hit hard for a couple of weeks before leveling out. My doctor said it's pretty common while you adjust to each increase. I eventually switched to tirzepatide for other reasons, but those appetite...

Anyone else experiencing brain fog on this stuff?

To Morgan2000 it has gotten somewhat better, but it still flares up, especially around my period. I've been on it almost a year now.

Your body is getting used to the medication. You'll probably see the effect ramp up around 5 mg. Make sure you drink enough water, eat healthy food, and deal with any constipation. The side effects can be tough. Down 80 lbs, maintaining for 2 years.

Absolutely fantastic!!!!

Semaglutide definitely worsened my acne right away. I woke up with several new pimples after my very first dose, which I thought was strange. It's still happening now. Just putting it out there as a 40-something who's battled acne since they were a kid. My sema doesn't contain any added B...

I'm still figuring this out myself. I woke up choking on vomit the other night. Walks, sipping water, or even chewing gum while walking helps me.

Telomeres *might* lengthen with epithalon, but we don't know if lengthening them actually extends lifespan. We only have data suggesting that short telomeres are linked to earlier death. Also, some of those at-home biological age tests aren't very reliable. You can test yourself twice at the...