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Second week now running Cagri on top of my 12.5 Tirz. Noticed appetite suppression right from that first .25 dose, though nothing to report weight-wise yet, added it mainly hoping to break through a stall. Probably still too early to draw conclusions. No negative reaction from the cag itself so far.

Personally I've noticed this medication (technically the higher-dose weight-loss version, same drug though) has cut way back on my drinking. Pretty much strictly a vacation drinker these days, could easily stretch six months or more before touching a drop again. When I do have one though, no...

Nearly two years on this medication now, and while I still eat far less than I used to, I can definitely manage more food than I could when I first started. Made a point early on to eat something sweet daily, wanted my habits to actually be sustainable long term and chocolate's just too...

Hi! Been on sema a little over six months now. Lost what some might call a modest amount, went from 170 down to 135 lbs. Might sound silly, but I really wish someone had warned me how quickly a face can thin out, mine changed at surprising speed. Roughly sixty days before the wedding I had a...

Bloodwork has improved dramatically, sorry to disappoint anyone hoping otherwise. Only downside has been my pulse climbing 12 to 15 beats per minute. Settled back down some since, though still running above my usual baseline.

Dealt with the exact same thing until I made the jump off semaglutide and onto tirzepatide not long ago. Way fewer side effects, no more that bloated feeling, and the weight's coming off again.

My pharmacy has a savings program they apply automatically that brings the price down to match the generic. Asked about it and turns out they'd already applied it by the time I picked up today.

That specific percentage reflects the average weight loss recorded across a major clinical trial spanning 72 weeks. It doesn't indicate any inherent ceiling on how much weight this medication can help someone lose.

Hey, a stall like this sometimes just means your body's found a temporary resting point, even after such a steady, quick drop before now. You clearly respond well at lower amounts, that's encouraging. Since you're already splitting a 15mg pen, a modest bump, say 5.5, 5.75, or 6mg, could be...

The ringing ears at 10mg/6d is a rare but documented side effect at higher dose frequencies. Whether it was dose-dependent or timing-dependent is hard to know without retesting at a different schedule. The sun sensitivity question in the OP's thread title combined with a massive result at 5'2"...

great result. the combination of dose calibration and consistency is what produces this kind of outcome without the miserable side effect burden that pushes people off protocol. you found the right pace

The UK private clinic telehealth-then-collect route is a real option for people who travel there regularly - the private system can see and prescribe in a single appointment for most conditions including weight management, and the medication can be taken home within personal supply rules. the...

the mismatch between what manufacturer documentation shows and what a third-party source is displaying is exactly the kind of discrepancy worth flagging - the Eli literature is the authoritative reference on what the actual product looks like, and any image that diverges from it warrants...

The shift from food taking up mental bandwidth to just... not is one of the things that's hardest to explain to people who haven't experienced it. Cookies in the house without thinking about them is such a specific marker. The OP's description of food occupying every thought is the before, and...

The low and slow approach anxiety when you see people starting faster and losing more in the early weeks is so common. The questioning that happens when other approaches seem to be producing faster numbers is real but the people who go slowly tend to have an easier time maintaining and have more...

Stopping tirz while at 8mg reta and evaluating independently for a month is the clean way to get a real baseline. Running both makes it hard to know which one is doing what. A month on reta solo will tell you a lot. What does appetite look like day to day since making the switch?

Low BMR from long-term deficit is the piece a lot of people miss. 2.5 years at 1200 and gaining at 1500 is the metabolic adaptation picture - the body is defending hard. Mounjaro tends to work differently than straight restriction because it's hitting the appetite signaling rather than just...

23.5 kg since December and 13.5 to go is a very different scale than 180 lbs total in the OP but the 'close to the finish line' feeling is the same. Almost there after never thinking it would work this fast is the part worth remembering when the last stretch slows down.

100 lbs in a year at a measured pace is actually a sweet spot that tends to minimize loose skin vs a very rapid loss. There will be some, there always is, but the strength work you do alongside determines a lot of how it looks. The health risk reduction is so much more important than the skin...

Ferritin at 19 is the clinically relevant part of that symptom picture - joint ache, restless legs, and early exertional shortness of breath all sit comfortably in the low iron presentation. The hair loss piece too. Before adding supplements, the typical workup rules out active blood loss as the...