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Not certain I count as a strong responder, though I began in April at 285 with a long term target of 180. Short term goals help me too, right now getting under 250 with just 5lbs to go. Way back at senior year I hit 220, which will likely be my next target after 250. I chose 180 because it lands...

Blame the scales, not yourself. Your reading shifts by the hour, by the day, by the week. No reading ever shows your true weight, since glycogen, meal volume, illness-related water, stress, poor sleep, muscle repair and so on constantly nudge it. So don't dwell on it. It's a tracking tool, and...

The $149 monthly figure is the manufacturer's entry price, medication included. That's oral Wegovy at the starting dose, and the price climbs to $299 from 9mg upward (I looked on Sep 7). What strength did they start you on locally?

Week two at 10mg for me. Possibly another week or two at 10mg to check whether the August plateau gives way, but 12mg is tempting, since it fits the phase 2 trial ladder of 2mg, 4mg, 8mg then 12mg better. This past month was rough, more so after 6mg and early 8mg went so well. Deficit plus six...

One option: reconstitute the whole amount, then split it across sterile vials. Suppose you wanted 60mg in 6ml. Put 2ml into the vial and recon, transfer that 2ml to a big vial such as a 10ml, top up with 4ml and mix well. From that, pull 2ml portions into fresh vials, which leaves a...

Worth adding that even without the scale moving much on this medication, it's genuinely been life changing. All my PCOS symptoms have cleared up. Inflammation's basically gone! It's honestly amazing! Even helped with my OCD symptoms too!

Could've stuck with the older diabetes pills, but instead talked to my endocrinologist about switching over. Didn't come across as a desperate last option once the research got read through. My doctors say organ function looks solid. Side effects stay manageable as long as you know the tricks...

On the whole 'did it take a while' question, the single-pathway medication needs roughly four to five weeks of consistent weekly dosing before it actually reaches a stable presence in your body. That's exactly the window you just wrapped up at the smaller amount. So the first month isn't proof...

A moderate amount worked best for me for a good while. The next step up barely made a dent, then going higher still worked out great. Some weeks the scale barely budged, but those small losses add up over time. Sorry you had to restart, but you've got this!

Would you actually call yourself someone with an alcohol dependency, or just someone who's lost interest in drinking since starting this medication class? If it's the former, probably not worth the risk, though only you can really weigh that. If it's the latter, go have fun. Just bear in mind...

Not totally sure what gauge my testosterone syringe is, but the result's the same whether I catch a nerve in the glute or not. When I miss the nerve, it feels no worse than a 30g needle. Today I held off on my BPC-157 and Tesa/IPA injection until nearly noon. Need to track down that peptide...

My A1C fell from 6.9 to 5.8 across just two months, and fasting glucose is steady between 100 and 110. My doctor's thrilled, and honestly so am I. And losing 50 pounds along the way certainly doesn't hurt!

Managed to get my mini fridge dialed in to hold a steady thirty-nine degrees! Decided to just go ahead and stash the backup supply in the freezer, tucked into a low-key container, keeping only whatever's currently in use in the mini fridge. That said, summers here hit around 120F, so that...

The doctor brought this one up just yesterday. Mentioned fewer side effects than the current medication, just at a higher price point. Congrats on those results! A consistent ten pounds monthly is genuinely encouraging! Still dealing with real hunger on this end.

These Reta wins are always such a good read. Running Tirz 7.5 alongside 3 Reta Friday and Tuesday, down 83 pounds across 18 weeks. My smart scale now puts me at overweight instead of obese. Everyone else here is genuinely inspiring. Hoping that even at 70 or 80 I still care about my health this...

Saw that too, genuinely interesting stuff. Not aware of anyone actually tracking GLP-1 or GIP numbers in their blood outside of a formal study. It does look like some people respond better to one drug over another based on their starting hormone levels, even though I'll admit the mechanism...

Been stuck in basically the same spot myself, just for a longer stretch. Held steady for the better part of a year. Wish it counted as maintenance already, but there's still more I want to lose. Finally decided to move up a step but couldn't track down anywhere able to fill that particular...

Don't quit that medication. Huge mistake if you do. You'll gain every pound right back, guaranteed. Stick with the smaller amount and just enjoy your life.

Have you noticed a shift in your stamina during workouts? Did 3ml right before leg day this morning, and even after a solid hour of heavy lifting, felt like I could've kept going. Genuinely noticeable difference. Could be placebo though.

Good for you! Does hunger ever show up? Just wrapped up the first month and lost eight pounds. The body now only tolerates a handful of bites per meal before signaling to stop. Getting hungry again shortly after triggers genuinely severe illness for two days, regardless of how small that extra...