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Apologies for the long post, but did tirz ever just stop working for anyone after a break? My start was dramatic. I injected a full 2.5 mg from the first pen and nearly landed in emergency care, my lower esophageal sphincter doesn't close properly to begin with. So I started over with microdoses...

Found myself a new go-to Reta, keep several sizes stocked up. Runs smooth, no complaints beyond the standard appetite crush, barely able to finish meals. That kicked in right away for me at 2mg. Sleep's still an issue though, working on sorting that out.

Feels like Mounjaro's given me options I never had before. It's not stopping me from eating the way I always did, but that voice demanding a beer specifically, or a whole bag of chips, or a chocolate bar, that's gone quiet. Snack urges still happen, minus the cravings driving them, so I can pick...

You look amazing, seriously. Hoping you feel every bit as good as that! Dropped 51 lbs myself in about 15 weeks on Mounjaro and I don't regret a single day of it. Got my life and my mobility back, and there's so much more still ahead. All the best to you.

Alcohol tolerance basically vanished overnight after the swap from mounjaro over to sema. Had one whiskey on the rocks roughly a month into the change and ended up parked in front of the toilet for hours, zero exaggeration there. Nowadays even a single drink triggers a genuinely awful next-day...

Probably tracks more with body fat percentage than the medication itself. My excessive sweating issue has improved so much since dropping this much weight. Before, walking into any heated space would have sweat pouring from me almost instantly, that transition from cold outside to a warm room...

Dealing with PCOS here too. Was on 7.5 and already losing steadily. Bumped to 10mg and dropped even more after that. Down half my total body weight at this point, currently holding at 7.5mg to maintain.

You look incredible, congrats! Mind if I ask, how long did the 50 pounds take, and how on earth did you dodge loose skin?

Blue Apron isn't a subscription for me, just order when I feel like cooking. 2-serving meals easily stretch to 3 or more. Tons of variety in what you can make.

Same here on the food noise stopping - that was the biggest shift for me too. And yeah, the anxiety drop was real unexpected. Feels so much better.

Nice work - did you end up with loose skin? How long did it actually take you?