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Understanding which pro-inflammatory cytokines contribute to your specific type of arthritis (or any autoimmune issue) is essential for identifying potentially beneficial peptides (and supplements). Monoclonal antibodies (proteins) seem to be the most effective in many instances, but I haven’t...

GLP meds usually decrease thirst. I've read studies about it. I drank around 8 liters daily and it halved on semaglutide and is the same on tirzepatide 15mg and 4mg of reta. I would suggest checking your blood sugar levels.

Some people don't see consistent changes until the second month. Don't give up hope yet! Sometimes it just takes a little longer for the medication to reach a therapeutic level in your system.

It's great you're noticing non-scale victories, Jules2006. Focusing on these can be as important as the numbers. Celebrating those small wins can be extremely motivating.

Awesome progress on the weight loss! You look fantastic!

Thanks for posting to the community! A quick reminder about the rules: We don't allow discussion of non-approved versions of semaglutide or any buying/selling of meds. Do not respond to anyone offering such via PM, as they are not endorsed by this forum. New to semaglutide? Check out the FAQ.

I've been looking into sermorelin/ipamorelin combo. I've been using a GHRP-2/Sermorelin combo from a well-known online clinic for about six months and it's been pretty good. My IGF-1 went from 100 to 200 and stayed there. I've lowered my body fat to around 16% from 24% and gained muscle...

Interesting info, good or bad, since I'm switching to reta from compounded tirz. One of the things I liked was the anti-inflammatory properties, since I'm basically at my goal weight. I thought the GIP was responsible, but it seems the cytokine effects are stronger for GLP1. Hope my results are...

Totally agree with BugGuy128. Diet soda gets a bad rap, but regular soda is way worse with all the sugar. People act like diet soda is pure evil, it's ridiculous.

Good info from Trail_05. I hit a stall around that same time. Weight loss started again. Down almost 70 pounds since December. Keep going. I aimed for 1 gram of protein per pound of bodyweight. Still do. Shakes or real food. I prioritize protein. Eventually I added about 150g of carbs a day...

Genetics, aging, and hydration play a large role in that. It's not DIRECTLY from the medication, but weight loss can definitely make it more noticeable.

You look fantastic! Great job 👏🏻

Keep up the great work! You look a lot like a celebrity I've seen.

Remember that muscle loss is a real concern! You're doing the right thing incorporating weight training Hank_25. It not only helps counteract potential muscle loss from the medication but also boosts metabolism, which is beneficial for long-term weight management. Plus, it's great for bone density!

Seriously, BOTH before and after are body goals! You look incredible!

Way to go! Studies have shown people can get off antidepressants and even reduce alcohol consumption! It also helps me concentrate. What's not to love about something that helps with addictions? And weight training is smart. You're young, but these meds can cause muscle loss, which happens with...

I'm curious for those of you who are seeing good results... How much exercise are you incorporating? I'm in my 30s and I keep hearing it's going to be nearly impossible to lose weight even with a GLP-1 if I don't hit the gym constantly.

That is awesome! Congratulations

Incredible! How long has this transformation taken?

Congrats on your success!