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That's a good question Bear_Fam. It seems like people have different experiences when trying to maintain. I've seen some people say they have to keep increasing the dose to get the same effect, while others do well on a very low dose.

From a research view, I get the placebo arms. But, to me, that's for those getting the placebo from the start. Not putting people on a life-changing drug and then taking it away. But, everyone eventually gets taken off the meds. No free ride forever. Is it better to have loved and lost than...

Yeah, it feels wrong to take people off meds, especially later in trials when we know the meds are safe and work. But we learn a lot from these trials, and people know about the placebo groups before joining. Still gotta suck. Imagine being on trizepatide for 9 months and then being taken off...

Thanks for sharing! Just to clarify, this article isn't about the actual SURMONT-4 trial, which was out last year. This is a new look at the Surmont-4 data, analyzing how heart health changed based on weight regain after stopping tirzepatide. To me, this chart from Surmont-4 always pointed to...

Has anyone seen this SURMOUNT-4 study? Basically, folks who were obese used tirzepatide and changed their lifestyles (cut 500 calories daily and exercised 150+ minutes weekly) for 36 weeks. Then, researchers divided them into two groups: one kept taking tirzepatide, the other got a placebo...

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For those of you just starting out, I've found that injecting on Thursday mornings helps cut those weekend cravings!

I combine sema and tirz myself. I inject them both on the same day. My hunger comes back around day 6 on sema, so splitting that dose also makes sense. I'm not too strict about the exact schedule. As long as it's consistent each week, it should be fine. Sometimes I'll add a little extra sema...

That's so true! I've been lifting heavier and seeing a difference in toning. You don't bulk up easily. It takes work!

I take a liquid collagen shot post-workout. 25 grams of collagen peptides per serving. That’s a lot for the price. Studies show that around 15g daily improved joint conditions in older adults. https://www.amazon.com/dp/B0734RHXS3

I'm so glad to hear about your success, FiberLean! I've been on a similar journey myself. Started around 410 lbs back in February, and I'm down to about 340 now. Still have a ways to go, but for the first time in a long time, I actually feel good about how I look. It's a game changer!

Way to go! Looking sharp!

You look fantastic! Great job!

It's funny, I'm now getting comments like "You're shrinking away!" It's mostly because people were only used to seeing me at a heavier weight. It's a little awkward, tbh. I'm just getting healthier!

I've been taking it for 9 months, and it feels like I've been gradually losing weight. Interestingly, I'm currently around the same weight as you are at 10 months! I'm glad it's working for both of us. 🫶🏻

That's wonderful! Thanks for sharing your journey - I think it is coming off slower than I anticipated. It is indeed working. I’m happy with any results that I get - but it is more gradual than I initially thought.

I really appreciate you mentioning the occasional weight fluctuations because I'm experiencing that this week. Hopefully, it's due to building muscle. Congrats, you look GREAT!

Wow! Any tips for someone just starting?

I remember when I was diagnosed with insulin resistance a year ago. Started with one thing then switched to something else. I started at 190lbs and now I’m down to 168lbs, in just 3 months. So happy.

First, you were beautiful before, and you're beautiful now. 'Ozempic face' isn't a thing. Weight loss changes your appearance, period. Your health is what matters, so ignore the haters. If you're happy with the results, that's all that matters! Congrats on before and after. You seem like a kind...