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When did you begin to notice the weight loss on the scale? I've been taking this for 2 months and will be on 1.0mg this Sunday. People have commented that I look smaller, but the scale remains the same.

Used SS-31 for 6 weeks then switched to Mots-C. Doing the 14-week protocol. SS-31 repairs mitochondria and Mots-c optimizes. Also take 600mg NR daily. Didn't feel much from SS-31 but Mots-C feels like progress.

That's my take, and what has been effective for me. Monday, Friday, Tuesday...

Eli Lilly (the maker of Tirzepatide) lists its half-life at 5 days. This means on day 5, 50% of the original dose is still active in your body. I switched to a 5-day schedule after reaching 10mg and developing a slight tolerance. I believe I could have stayed at a lower dose if I'd done this...