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Glad we're talking about this. Yeah, it stopped working for me too. And eventually, a tirz did as well. I think that's just how these things go. I tried cycling off and on, but they were even less effective the second time. I don't think they're the lifetime fix they're made out to be...

Off topic but your kiddo is adorable!

Wait, so you started a semaglutide back in 2020, got to your goal weight, stopped the injections for a while, and then gained 45 pounds back? Now you're injecting a semaglutide again, paying out of pocket, hoping to lose weight again because your insurance doesn't cover it?

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I liked the dog study too. We're closer to dogs than mice! From that review:

If you mean the MMPOWER-3 trial: https://www.google.com/url?sa=D&q=https://ojrd.biomedcentral.com/articles/10.1186/s13023-023-02986-x It showed some benefit in specific genetic subtypes. Some human studies *did* show good results. Like this one on heart function...

You'd basically need super expensive tests to know if it helped at the cellular level, and even then, you wouldn't be 100% sure.

Oh yeah, alcohol can totally do that! I've heard Pepto helps. Maybe try that?

Congratulations! You look fantastic. You kept your curves too, which is my goal (though I could use more 🍑) Sorry to hear about the health problems though. It's something that needs more discussion, especially since this drug is prescribed to many with disordered eating, little nutrition...

That's an awesome result!😍

Great work. Congratulations. I wish I could see the same results.

Yes!! Congrats!!! You're inspiring me to keep going. I lost about 55 pounds in my first year and want to get rid of another 45. Appreciate you, OP. Well done.

If you have one of those scales at home, make sure it has good batteries. I saw on Reddit that dying batteries can cause the scale to give false high readings.

Fingers crossed your stall is done. I also like to keep my amounts low. I'm only on 3mg of something else and even with some cravings, I don't plan on increasing. How much do you weigh? 1100 calories is a very low number of calories, like a body builder prepping for a show. You may have slowed...

My wife and I needed different amounts of tirz from the same source. 10mg/week was too much for me due to some side effects. I reduced back to 7.5mg/week and am almost at my weight loss target. My wife uses 15mg/week. Her side effects are minimal, but her weight loss has been slower than mine...

I hear you. That's what happened to me with Ozempic. Switched to Mounjaro a month ago and it's working great!

Way to go!

Amazing results! What's really striking is how much younger you appear.

For those who are wondering, the test results came in yesterday and were positive. It was slightly stronger than 20mg with 99% purity. Testing is always the best way to be sure.

Thank you. That's reassuring. Our vial is on its way to a testing facility.