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I'm not even 72 hours after the first dose and I feel I'm back to normal. It's still early and it hasn't built up in my system, and 2.5 isn't therapeutic, but I secretly hoped I wouldn't have to really struggle after the first 48 hours seemed so promising!

This totally happened to me when I was on Ozempic. Every time I went up a dose, the food cravings hit hard for a couple of weeks before leveling out. My doctor said it's pretty common while you adjust to each increase. I eventually switched to tirzepatide for other reasons, but those appetite...

Anyone else experiencing brain fog on this stuff?

To Morgan2000 it has gotten somewhat better, but it still flares up, especially around my period. I've been on it almost a year now.

Your body is getting used to the medication. You'll probably see the effect ramp up around 5 mg. Make sure you drink enough water, eat healthy food, and deal with any constipation. The side effects can be tough. Down 80 lbs, maintaining for 2 years.

Absolutely fantastic!!!!

Semaglutide definitely worsened my acne right away. I woke up with several new pimples after my very first dose, which I thought was strange. It's still happening now. Just putting it out there as a 40-something who's battled acne since they were a kid. My sema doesn't contain any added B...

I'm still figuring this out myself. I woke up choking on vomit the other night. Walks, sipping water, or even chewing gum while walking helps me.

Telomeres *might* lengthen with epithalon, but we don't know if lengthening them actually extends lifespan. We only have data suggesting that short telomeres are linked to earlier death. Also, some of those at-home biological age tests aren't very reliable. You can test yourself twice at the...

My journey started similarly, and I also have PCOS! I lost most of my weight on .25. I still only take .25 for two weeks and then increase to .5 for two weeks each month (helps with hormonal cravings). I’ve dropped 35lbs and want to lose about 5 more. I’ve never had side effects.

I've been on .25 for about seven months and have lost approximately 45 pounds, which I'm happy with considering my age. I tried the .5 dose for a few weeks as prescribed but it made me feel terrible, so I went back to .25. I plan to stay on it. Besides the weight loss, Ozempic has really helped...

Recent research has shown a U-shaped curve for mortality related to IGF-1. Optimal levels seem to fall in a pretty narrow range, around 150 ng/mL.

I agree with T2D_Survivor_Mark, it's incredible what these meds can do, especially when combined with lifestyle changes. As a healthcare professional, I've seen firsthand the positive impact on patients with Type 2 diabetes and weight management. Keep up the great work, everyone!

Good point, HormoneHacker

Look into a temp alarm! I have one on my big freezer, and it warns me if the temp is off. Gives me peace of mind.

You guys are both adorable in both pictures!

I saw this online: Some compounded versions of semaglutide/tirzepatide are stable for 3-4 weeks at room temp (under 85F) *after* mixing. So some people don't refrigerate at all after mixing. Hope this helps! You may get even better advice from other people here.

Fantastic!

You both look significantly healthier now.

Awesome job! I started around 225 and I'm down to 190 as of today. Tomorrow's my 13th injection. Still hoping to lose another 20-25 pounds – my goal is to be around 165-170.