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I think the advice from ReconFree is spot on. If you think you might want skin removal surgery down the road, definitely document everything. Insurance can be a pain to deal with.

Not much science on cycling these off and on, mostly just what people share. But evidence points pretty hard at restarting being less effective and needing way higher doses to kick back in. Recent rat study on the forum about stopping and restarting.

I've had atopic dermatitis since I was a kid. Dermatologists didn't help much, but a friend suggested a shower filter. Turns out our water was the problem all along. It's full of stuff that was drying me out. I moisturize twice a day and use a light, shea/jojoba sugar scrub 2-3 times a week to...

That's great news, ShrinkAF! It's amazing how much these meds can improve overall health. Have you seen any improvements in other areas, like blood sugar or cholesterol?

Lifelong eczema/skin allergy sufferer here. We've all heard it a million times, but drink lots of water. You have to hydrate from the inside out. Otherwise, even the best lotions won't cut it. If you're scratching to the point of bleeding, go to the drugstore and look for products with urea...

You go, girl! Woo-hoo! 🎉🎉🎉

I had the same issue with Tirz! Found that topping my syringe with a unit or two of plain bac water, then injecting slowly and splitting the dose—did half one day, half the next. Five months in, no more lumps. Finally!

felt it in 30 minutes on my 2.2mg starting dose. food noise cleared, appetite tanked. titrated to 4.4 and staying put. tracking cico the whole time. weight's falling off.

some weeks i swear the suppression just vanishes—like i shot nothing. then boom, it's back. freaked me out the first time but now i know it's just how things cycle. haven't heard of anyone losing it all while staying on, so i'm cool with it.

Technically you might not know until tomorrow morning. The half-life is short but effects linger, so a 0.5mg+ top-up might be smarter than a full dose within 24 hours. 2mg seems too high for anyone. As a guy, I'd stick to 1-1.5mg max within 24 hours. The dosing is the biggest PT-141 issue since...

if you're still snacking try 2mg next week - that's the starting dose in trials. by then your serum levels stabilize and the med's more consistent each week. might not need higher doses unless hunger comes back or you plateau. i personally topped out at 3mg and spent most of my 12-week run at 2mg.

i log every dose, date, side effects, weight, and dose changes in a txt file so i can track everything and find patterns again.

Following up on that's a great idea! I'd worry about temperature fluctuations during travel; a dedicated sensor compartment is smart.

I like the four-pen option for travel, but could it be insulated at all?

Your transformation is amazing! You should be incredibly proud of yourself. ♥️

Very neat!

My progress has been gradual as well. I've been on something similar for about a year now, and I've only dropped around 30 pounds. Went from 230 to just under 200. I'm looking and feeling better, and my blood sugar is way better. I just wish it was faster!

I recall reading a reminder, and it was about how we don't need to eat the whole plate of food. I need to remember that. I feel like I still eat more than I need to sometimes!

Just amazing! Beautiful.

Thanks, everyone, for the feedback! goal-weight-or-bust, yes, my doctor wants me on both meds for now.