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Three years on Ozempic and then watching it stop working is a pattern that leads a lot of people here - the dual mechanism in Mounjaro is specifically what tends to pick up where sema stalls. Appetite suppression on the early doses is usually modest; it builds with time and often feels more...

The mental load of eating on these meds flips from craving management to nutritional optimization - one is involuntary and exhausting, the other is chosen and exhausting, but the chosen version has an endpoint when the habits become automatic.

316 to 252 is 64 lbs and it's showing in the photos. The vial trickle after withdrawal is a pressure artifact from the reconstituted peptide - not a meaningful dose loss, just residual surface tension at the needle site. The face and body change at that scale is real and other people see it...

I've been on .5 for about a year and a half now, Happy_Fixed851. I've lost 68 pounds that way. I probably could go up but I don't want to so I won't. I'm maintaining well.

I've lost 48lbs on .25mg since last June.

I've gone from 187lbs to 143lbs, and I've been able to stay at 0.5mg this whole time!

Related to this thread of gratitude, I found this on Reddit: a woman there lost a significant amount of weight and looks years younger!

I've been getting a slight rash at my injection site the last couple of weeks. Anyone else experience that? I've been on sema for over a year, using the same needles and alcohol wipes. Never had a problem before. Should I be concerned?

Congratulations!

They probably lost millions due to the extra priming volume. This is likely a cost reduction on liquid waste.

The transformation speaks volumes! And those legs are looking great! 😉

It probably just got buried in their messages. Try again after the holiday. Or find a vendor with a US warehouse. They're usually still processing orders during the holiday.

You didn't mention how you contacted them for either order. Was it through a message, or email? Did you start the conversation, or were you replying to a message? And who were you trying to order from? Someone here has probably dealt with them before and can offer advice. After the holiday rush...

Pausing Ozempic, huh? I've been thinking about lowering my dose, but the shortages have me worried. Someone said they gained 10+ pounds in a few weeks just lowering their dose. Staying vigilant!

When people stop glp meds, like with other weight loss methods except surgery (and even then, regain is common), they'll usually regain the weight gradually. Only a few keep it off long-term, <5%. Most will return to near their starting weight. This has been shown in many papers. I've seen that...

Statins significantly lower naturally occurring GLP-1 levels (and have been found to increase diabetes risk and plaque calcification). I'm not sure how that would affect GLP-1RA efficacy, unless it makes it harder to maintain weight loss after stopping GLP1 drugs.

Was that doctor completely unaware of the potential for muscle loss prior to January 2025 (when the article was written)? And did he really not realize these meds are viewed by pharma as ongoing subscriptions, not cures? LOL, maybe he should stick to what he knows and let folks with better...

For those of you just starting, don't be discouraged if the scale doesn't move immediately. I've seen some people take a few weeks to really respond to the medication. Stay consistent!

Wow, that's like shedding an entire person. OzempicFace, how does it feel to have lost so much?

I am so excited for you and your progress! I can't wait to get under 200 myself. Awesome job!!