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Vial volume and concentration relate - 5mL vs 1mL at the same mg gives very different draw volumes per dose. On a smaller vial, priming loss matters more.

50 pounds on Mounjaro since October with 13 left is exactly the phase where the mental component becomes the dominant story - the physical scale number matters less and less when the daily experience has shifted this much.

Klow supply is inconsistent - locking in tirz now while it's reliable and adding Klow once supply stabilizes is the lower-risk sequencing for the combination.

The pen is supposed to be good for about 56 days after you start using it. Some people say you can go up to 100 days if you keep it cold. But you'll probably increase your dose soon anyway.

From a biology standpoint, it's a better idea to reduce the dosage while sticking to a 7-day schedule. Stretching the doses by a day occasionally is fine for things like travel. The 7-day thing is about how the medication peaks, its half-life, and keeping a steady level of it in your system.

started semaglutide and sometimes get this sudden dread with nausea and fast heart rate, feels like a panic attack coming on. then i have to go to the bathroom and boom, suddenly fine. not urgent like emergency bathroom but there's definitely a link. took me forever to figure that one out.

I saw someone post that they lost 80 pounds and have kept it off for over 6 months after stopping semaglutide. It's always inspiring to see success stories!

I've been stuck at the same weight for three full weeks now. I've been having heartburn and other stomach issues. I'm barely eating anything. Maybe this doesn't work for everyone?

I'm not a rapid loser either but down about 28lbs after 17 weeks. I'm roughly a third of the way to my goal, currently 218 after starting at 248, hoping to get to 155. I'm 56yo F, 5'8", and have thyroid issues. My dose is 1mg. Congrats on your success!

Yes, in a way. I just recently went back on Ozempic, but I was on Mounjaro for about a year and a half and lost about 75 pounds. Then I had to stop for 8 months because of insurance and job issues. I gained back about 10 pounds almost immediately (within a week), but then nothing more. I'm back...

I feel you! I've wasted too much of my life obsessing about food. This stuff lets me focus on things that actually matter.

You go!!! 👏🏻👏🏻👏🏻👏🏻

I'm annoyed by doctors who are so judgmental about medications. I saw someone mention their doctor shaming them for taking semaglutide, saying she's losing baby weight "the right way" with diet and exercise. Doctors should be supportive, not make people feel bad! So unprofessional.

I have a family member who is your age and weight and lost the weight and is now trying to lower the dosage. Who knows if it will work, but your doctor and weight loss clinic failed you. Just try it and see! Get the meds, see if they work, change your lifestyle, and then lower the dose once...

Interesting. I've noticed the opposite. Things I used to think were perfectly seasoned now taste bland. It's like my tastebuds are recalibrating.

Some of the comments here are off base. People don't just "successfully lose weight and keep it off" all the time. Most people who lose weight through diet and exercise alone gain it back. Obesity is a chronic and complicated condition. So, yes, make healthy changes, because you'll need to even...

Ice cream. Any kind, but especially vanilla bean. My system *hates* milk these days.

Oh man, where do I even begin? I was all about the sugary cocktails, breakfast mimosas, and ALL the pizza. And candy? Don't even get me started. I kicked refined carbs and sugars to the curb and said goodbye to 140+ pounds. Now I can indulge every so often. But the booze? Still not there.

Lots of water, and watch your fiber intake. Too much fiber can sometimes make it worse.

Good for you! Keep it up.