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The timing with the food you ate makes it worth considering. GI stuff from the meds usually hits within the first day or two after injecting, not right after eating specific food. That said, your system is already sensitized by the meds so bad food hits harder than it would otherwise. Both can...

Protein and volume are the framework. Greek yogurt, cottage cheese, chicken - high protein, low calorie density. The medication handles appetite, you handle food quality. Even rough calorie tracking for a few weeks reveals the patterns quickly.

A hundred pounds on Wegovy is an absolutely huge achievement. What dose did you land on for the final stretch? And how did your eating habits evolve over the two years?

Congratulations!

Great work! Can you tell me about your current diet?

Word of caution to everyone, especially those straining due to constipation: be careful! You don't want to end up with diverticulitis. If you haven't gone in a day, try something gentle to get things moving like coconut oil. Trust me, you don't want diverticulitis.

I identified it. The concentration is small... but it's there. It's not PFOA, but anything with PFAS stays in your body for a while. They're very stable and hard to break down. I don't know the source... maybe the rubber seal (though rubber shouldn't have PFAS) or the manufacturing process...

I've accidentally skipped a week when traveling. Didn't change much. I think it's still in your system. I definitely didn't get ravenous.

One freeze cycle with mixed Tirz should be fine. And if I tell you that I find PFAS in all the samples I analyze, and no one discusses it here? The analyses I saw are only for targeted compounds like Tirz or Reta. I never saw a chromatogram and tried to identify unknown peaks. After a "good...

Freezing reconstituted? I'm not sure about that. Any refs on freezing?

I rotate GLP-1s through the week. I'll slam 6mg Tirz on Fridays, then 3mg Reta on Mondays. Splitting doesn't have to be the same med or half the dose each time.

I took my starting dose every 6 days, and I stayed on that schedule until I got up to around 5 mg. Then I stopped craving food right before my next shot, so I switched to 7 days.

Degradation is a thing, so I go by 6 weeks max. After that, I deduct 10% per week for degradation.

Yeah, 6 days is totally fine. Some even do it every 5 days. Or, split the dose -- half every 3.5 days. That keeps the cravings away for me.

The cartridge seals in pens are made of the same stuff as vial stoppers.

Meh. I'm keeping my autopens.

I had one pen that broke apart mid-injection, but I don't use it anymore. All my other models have worked well. I really like using pens.

I love my pens. I take several peps every day, plus some once a week, so pens save a ton of time. Plus, there's less chance of contamination than drawing up a syringe daily. Also, the needle isn't dulled from going through a vial, so it's more comfortable.

Will do this. I really want these to work. I hate prepping shots all the time. I have one of the V1 models.

Sounds like a good way to test my pens! Thanks.