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In my late twenties I dropped 90 lbs over roughly 18 months, and skin trouble never became a big deal. The belly is where extra skin shows most (reminds people of a postpartum tummy, and I have never had a baby). A perfectly flat stomach is likely out of reach, and honestly Im fine with that...

5.5 years on GLPs so far: first sema, later tirz, currently reta. Three BP meds at the start, now just half of a single pill. Blood pressure fell over time, 160/90 down to 100/60. My pulse crept up, 70 to 80, though I feel fine.

I just bought a thermos-type bottle with a freezable insert that supposedly keeps 2 MJ pens with awkward shapes cool for about 72 hours. Havent tried it yet. A wireless temperature probe will go in there so I can measure how cold it stays over time. Should it miss the advertised performance, I...

Paid for bigger boobs a couple years back. Now Im glad, because thats all that remains. Whatever fat sat in there has vanished. Muscle is my plan to refill the butt area, since all the padding back there vanished as well. I blame TRT, I think it decides which fat survives and which doesnt. My...

According to the studies on reta, youre probably already past the effective range. The benefit topped out near 8-9mpg. Youre likely hitting a different roadblock that reta cant address. Personally Id look elsewhere instead of raising the dose.

I felt no hunger from about day 2 after the injection. Thoughts about food remained, yet real hunger was gone, and eating gave less of a reward buzz. Strange to find food no longer ranked as my favourite thing in life.

A sudden cardiac event started this for me, and at the same visit doctors found T2D plus fatty liver among other things. My doctor felt Mounjaro could help on top of the usual treatment. Since 2.5mg gave me nothing bad including alongside my remaining prescriptions, she opted to go higher and be...

Mine was similar. I also started at .5 and skipped the .25. Turns out its delicate. Slight overeating triggers severe nausea, and so does undereating. I experiment with foods and portion sizes to see what my body tolerates. Oddly, steak wins, even a cheap cut, seared in a pan with salt and...

Noticing my body reshaping more than the scale actually dropping. A friend's told me the same thing. This drug class targets fat specifically, not muscle, and does it well from what I've seen. Not sure where exactly the fat goes, but my clothes are definitely looser or falling off now. Been on...

How long did it take you to get down to 118? 165 feels like the right stopping point for me. Congrats on the loss, and the gain too, that's fantastic!

Year-long user of the dual-action medication here. Running 15mg weekly. Took a dose of the third compound yesterday afternoon (about 14 hours ago now), mixed with 2mL of bacteriostatic water. Came out perfectly clear. My next dual-action shot is due Thursday. Idea was to time this new addition...

Just took my very first injection last week, but I've shed 75lbs total over six years. Only dropped a single clothing size and honestly look nearly unchanged. It's incredibly frustrating, went from 316 at my heaviest down to 241 currently. Practically no visible difference

Tried it both ways, subject to change, but air's my current go-to method. If that 13mm dead space works out to .15ml, and I'm mixing at 30mg per ml, that's roughly 4.5mg sitting in the filter, or about a dollar's worth of reta wasted. Here's another angle worth considering: Sixty milligrams of...

How long did the process take for you? Standing 5'2" at 156 currently. Got my very first Tirzepatide dose yesterday. Hasn't dipped below 145 in ages for me, keeps coming back after I lose it.

Everybody responds differently here. Titrating upward doesn't guarantee a faster drop. If anything, it might just guarantee some unwanted side effects, though you're probably already aware of that. Is your appetite actually suppressed? Feeling fuller these days? I'm a slower responder myself...

This particular one has caught my attention ever since I got into weight-loss peptides. What worries me is winding up lumped in with the fringe conspiracy crowd. Skepticism toward pharmaceutical companies makes sense to a point, but plenty of people approach this subject with way too little...

Same here. Without staying consistent, I slowly regain whatever comes off in the days right after each injection, guessing it's inflammation-related fluid, maybe something else too. The exact cause is a mystery even to my doctor. Not much research on it yet. So I'm running a moderate amount...

Do this too. For hygiene reasons, given you'll be drawing from it well past four doses and the usual 30-day window, handle it the same way you would a vial and pull your amount out with a small insulin syringe, plenty of tutorial videos online demonstrate the exact method.

Yeah, no worries at all. First time mixing anything I meant to add roughly two milliliters, but instead accidentally spilled some diluent onto the counter, most of it made it into the vial though, so I just estimated I'd landed around 1.6 milliliters into my twenty-milligram vial. Lost weight...

I'm roughly twenty years further along than you but started this specifically for kidney disease. Kicked off at .25 for four weeks, still holding at .5 now, eleven weeks total, went from 178 down to 159 so far. Working within a calorie deficit the whole time though, mostly plant-based but I...