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Just wanted you to know others feel this way. A week has passed since your post, hope things are fine. I take these meds myself, after decades of yo-yo diets; I went from 190 down to 132-135 over 4-5 years, and at 4'11" I'm pretty content with where the scale sits. Hopefully a solid healthcare...

58M, 6'. Started reta 1mg on 1/30/26 at 217lbs, with BPC, TB and also GHK-Cu running. Lower appetite, low motivation. 2/13: 211, up to 2mg after two weeks, clearer appetite drop, nausea, some lethargy, so more protein, psyllium and magnesium. 3/6: 200, went to 3mg, felt nauseous and unwell...

About to place my very first order for the third compound this week. I've got roughly 35 kilos to lose, a lot of it visceral fat. Works out to about 32 percent of my current weight. Understand this could realistically stretch across a couple of years, depending heavily on the dosing schedule...

Running reta at 4mg weekly. Tend to chase dopamine pretty hard normally, so this drug's mild flattening of that pull has actually worked in my favor overall. Your results may differ though.

Coming up on a full year with Mounjaro myself. Totally agree that home cooking or dining out doesn't have to feel like a chore. Make something you actually enjoy and just save whatever's left.

Babe, you're still gorgeous, don't stress about it. Also, massive congrats on how far you've come!!! I'm on my own weight loss path too, and yeah it's bittersweet letting go of favorite outfits, but I love treating myself to new pieces, or digging up old ones that never used to fit. Xx

This stuff wiped me out and threw off my gym routine for a while, and not in a good way. Now five months in, it's evened out. Getting back to the intensity I actually enjoy. Early on it genuinely worked against my goals, even put on some weight at first.

Seconding thrift shopping, dropped 140 pounds myself and went from a size 22/24 down to 8/10 depending on the brand, thrift stores have kept my closet stocked the whole way. Don't shy away from getting pieces tailored either!

Cycled through both compounds at different points. Reta broke through a three month plateau for me, but the constipation got worse and the emotional flatness was more noticeable. Went back to sema for maintenance now.

Only ordered two kits of that compound myself, 50mg vials, and both looked identical as powder and once mixed. Would definitely reach out to whoever you bought from, like the other reply suggested.

Might be better to frame it around blood glucose control rather than appetite or weight loss, especially since it was prescribed for type 2. Something like saying you think a higher dose would give better glucose management.

So well put! Whenever this topic comes up, I always mention how peaceful things felt once the constant food chatter finally stopped. That's honestly the biggest miracle these medications have given me.

Have to push back on that framing. No doubt it's the case for some folks, sure, but that's not how it's supposed to work. A possible side effect? Sure. The expected mechanism for losing weight? Absolutely not.

Taking oz for diabetes here. So basically weighing a small risk of one eye condition against a much bigger risk from diabetic retinopathy if I don't.

100oz is roughly where most people need to land when on GLP-1s - the hydration target goes up because the medication blunts thirst signal the same way it blunts hunger. Yes, you'll be urinating more for the first week or so as the body adjusts, but it normalizes.

PCOS plus first dose Sunday is such a similar starting point to the OP that the twin comparison is real motivation. The OP's journey from lowest to highest dose and then every other week maintenance is the full arc of what you're starting. Congrats on day one - keep notes on how the first few...

1.5 to 2mg for active loss and then stepping back down toward a 0.5mg maintenance is a thoughtful calibration approach. The titration down tends to be slower than people expect - the body takes time to find the floor where hunger stays managed without the full therapeutic dose. What timeframe...

postal worker theft is a documented alternative explanation for packages that show delivered but aren't there - the carrier infrastructure has enough individual variation in handling that theft at the last-mile stage is not rare. it's worth distinguishing the 'delivered then stolen' scenario...

Counting calories and finding what actually works long-term is a real lesson that doesn't always come through until after the GLP-1 chapter. The 80 lbs in 18 months in the OP is remarkable and the not-quite-done piece is familiar. What did the calorie tracking reveal that the medication was...

3rd shot at 1mg and already feeling it from the day after the first is the early responder experience that makes the first few weeks memorable. The OP's face gains showing up alongside slow overall progress is the common recomposition pattern. Getting protein in when appetite is that suppressed...