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278 to 180 in 7 months on reta is in the top tier of responses - the lean mass preservation question is the right one to ask at that pace. The 153lb lean figure held from 257lb to 238lb is the critical data point; tracking it through goal weight is what separates a good outcome from a great one...

Part D coverage for GLP-1s is still in flux - the details vary significantly by plan.

Keeping it quiet is common - results tend to speak for themselves without needing to explain the source.

I've seen some users mention that hunger can fluctuate, especially early on. Someone on Mounjaro said they really felt the effects the first few days and then it waned a bit, but leveled out after about a month. It might just take some time for your body to adjust. They suggested making sure...

Are you losing weight? If the point is to reduce and you're achieving that, why consider upping the dose?

Yesterday I put away a 500-calorie bag of Nerd Clusters... it was a choice, but still. I don't need to be doing that.

You look incredible! Must feel amazing!

Fantastic work! 🎉

Congratulations!

That's a good reminder that these drugs aren't a permanent fix. You still have to maintain a healthy lifestyle even while taking them, or the weight can come back.

I haven't tried Reta, but I've used Mounjaro and it was incredible. Semaglutide did nothing for me but Mounjaro was amazing. Life changing, no sides, felt normal, felt like I finally had control. Reta is meant to be even better... So why not start on Mounjaro and have the ability to step up? I...

I agree with Ratched77. Filtering is cheap insurance. Why wouldn't you?

For those of you using GH peptides, has anyone here been diagnosed with empty sella syndrome? If so, do secretagogue GH peptides work in your case? I am undiagnosed, but curious.

That "exposure to unstable compounded formulations" line is just the usual bashing of compounded GLP-1s. Probably paid for by Eli Lilly. I doubt peptides are any less stable than brand name stuff. I've been using compounded tirz for over a year, and it works great, even better than Zepbound...

Start with tirzepatide, then switch to reta if you plateau or have side effects like fatigue that don't go away. My reasoning: Tirzepatide works really well for many people, and we have years of data on how safe it is. Retatrutide is promising, and I'm sure it'll be proven safe once the...

I took 150mg/day liquid for approximately 3 weeks, followed by 200mg/day chloride capsules for 2 months. I combined this with TMG and NR, but it did not have a positive impact.

For any of you on sema or tirz, are you finding you're less tolerant of alcohol? I've heard from some patients that they just stopped drinking because they didn't enjoy it anymore or had bad reactions.

You look great 👍 👌

The best thing is getting rid of the old clothes and buying new ones!

Maybe 15 weeks now?