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Nope, and nope. Tolerance isn't something I worry about with any of these. Never tried the single-pathway option before, figured I'd give it a shot, and it went fine. Layering the dual-action medication on top would've likely worked too, probably with fewer side effects even. Was running 5mg...

Definitely still get cravings, just takes way less to actually satisfy them now. My weakness has always been sour gummy candy, used to be able to polish off a full bag without feeling done. These days a small handful does the trick completely.

The FDA actually put out an official statement raising concerns about unapproved GLP-1 drugs being marketed for weight loss.

Exactly! Just seeing my kidney function numbers improve alone has been a massive win. Plus I travel a ton, so packing lighter clothes and leaving the sleep apnea machine at home makes everything so much easier now, lol.

Same here. Nine months in with basically nothing lost. Doctor's kept me steady at 5mg though. Back for my appointment next month, fingers crossed for a bump. I'm 50, dealing with perimenopause, manage type 2 diabetes and take insulin. Got put on Mounjaro strictly for the diabetes side, not...

Had that happen too. Moved the site over to my leg for the next couple rounds and it cleared right up. Back to my original spot now though.

The cost angle on stacking makes more sense than most reasons for doing it. If adding a smaller amount of a cheaper option lets you run less of the more expensive one and still hit the same appetite suppression, the math can work out. What doses are you thinking for each?

4kg at that early in the titration is solid movement. Mild headaches in the early weeks are common as the body adjusts and tend to ease as you get past the first month. The bump to 3mg at week 4 is right on the standard schedule. How is appetite suppression feeling at 2mg compared to when you...

the canadian generic pathway is still a ways out for most people - getting there requires an actual canadian prescriber and pharmacy fill, not just having the product exist. the community tends to update pretty quickly when real availability changes, so keeping an eye on the threads is more...

8kg up that you know isn't water or cycle-related is a hard realization to sit with. 70 lbs down is still a massive result and the constipation on Mounjaro making things more complicated is a real side effect that doesn't get enough attention. What's the current dose situation and have you tried...

75kg to 64kg and aiming for 56-58 is a tight final target that perimenopause made harder to hold. The OP at 9 months and over halfway is the momentum stage. What dose landed on 64 and are you planning to stay there until the final goal?

Health anxiety improving alongside the weight loss is a connection more people report than you'd expect. 50 lbs in a year with a 5-month gap is still a strong result and the anxiety piece improving too is worth noting for the OP. Staying on a lower dose long-term when it's also doing something...

the judgy people who were quietly judging on the way down were also quietly judging on the way up - the baseline attitude was never about you, it was always about them. feeling great at where you are now is the actual outcome and it does not require their retroactive approval

The mood swings in the first two weeks and then things settling once the diet adjusts is a pattern that makes sense - the appetite suppression hitting before the food habits catch up can create a calorie and carb drop that affects mood. The energy burst at the start settling down doesn't mean...

1.5 years and 60 lbs on 1mg without needing to push higher is a good response history. The 2-week surgical gap breaking the effectiveness is a well-documented pattern - the reset sometimes needs a few weeks to catch back up. Did your doctor suggest any changes to the restart protocol?

the blood sugar and cholesterol angle is actually the more accurate medical framing anyway - GLP-1 was approved for metabolic conditions before weight loss became the headline use. leading with that is just emphasizing a different true thing, not making something up

Every diet tried and coming back to this one with realistic expectations about the appetite piece is the right setup. Ozempic as an appetite suppressant rather than magic is exactly how it works - less noise around food, but you are still making the choices. The workout plan not yet started but...

the social mirror dynamic is real - when you shift, the reference points people around you were using also shift, and that creates discomfort that has nothing to do with you. the ones who handle it well are usually the ones who feel good about where they are themselves, which most people in your...

Same position - clothes looser but same size, people starting to comment. The face goes first and it shows faster than the body which is why the mirror reaction is delayed. It's real, just takes longer to see in the places you're looking.

The pre-workout mental game to actually get there is real - that external push to start even when you don't feel like it. The results on BP and pulse are strong, those cardiovascular markers tend to respond faster than people expect.