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A year of dry hands even with lots of water usually isn't about hydration. I'd look at soap and hand washing, and put a thick ointment on right after each wash. Same for the bumps on your legs: keratosis pilaris tends to respond to a lotion with lactic acid or urea, no peptides needed.

Thursday night is my shot day for this reason. I follow a GLP-1 specialist on youtube who says fast at least 8 hours after the shot for best effect, which is why I inject right before bed. Also, next week I'm going from 0.5 up to 1mg.

What's different for you specifically? Haven't run into much myself besides occasional mild nausea here and there.

Appetite dropped completely at 2.5mg but came right back once I moved to 5mg, and it's stayed that way since. Genuinely not sure why the appetite returned. Still eating less overall since I fill up faster, but even a little hunger feels bizarre while on mounjaro, not a sensation I'm looking to...

You just know sometimes, you know? Suspected as much myself, though not many people seem to agree. Genuinely interesting. Also willing to go along with the good-enough unofficial option for now. Really hoping pricing comes down significantly soon.

Also just went through my initial follow-up visit. Type 2 diabetic here, dealt with gastroparesis long before starting this. Spent 11 weeks at 2.5 and only saw 6 pounds come off. Honestly leaning toward slow and steady being the better path anyway. Doctor bumped things to 5 though, waiting on...

Might be worth trying daily facial creams, gentle massage, or scraping tools and seeing if that provides even a little help, though staying consistent with it matters a lot.