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338 to 285 in six months is real. The debate about these meds misses what the people who actually use them know - the medication creates the opening, the person decides what to do with it. 53 pounds is what doing something with it looks like.

2,760mg in the freezer is a serious stockpile. The R60 versus R30 question comes down to reconstitution frequency preference.

The new KwikPen design removing the extra dose is a real change for people who relied on that fifth draw. The leftover pens are worth holding onto if you are still using the old format. The generous offer for NL folks makes sense given the timing.

I'm also 5'7 and started around 215. I felt a little too thin around 150. But I'm in my 40s, and I think a few extra pounds fill you out as you age. I'm up to 160 now, which was my original goal, and I feel good. You have to decide what looks and feels best for you.

Maybe you have body image issues, and your family is genuinely worried? Just a thought... if EVERYONE's saying it, maybe there's some truth to it.

That's encouraging! I'm on the lowest maintenance dose and it's still working for me.

It's for nausea. I only needed it a few times when I first started, but everyone is different!

I'm smiling so much in both pics!

I started taking sema at the tail end of May '25. My starting weight was 257, my initial goal weight was 199, and guess what? Current weight: 199! The worst of it was some upset stomach and feeling queasy, but antacids and anti-nausea meds took care of that. Now I'm shooting for 175, which I...

Wow, [USER=GeneProgress] that's amazing progress in just over a year! I'm hoping to have similar results. What side effects have you experienced, if any?

Way to go! Fantastic progress.

Happy Birthday 🎂 🥳 🎉

Awesome job! I know how awesome that can feel! Last spring I finally got below 300, for the first time in two decades I think. Now I'm down to 215. This med is really doing wonders.

Happy birthday to Mr. Confidence himself! Sounds like you're killing it, and looking fantastic while doing it. What a way to celebrate!!! Huge congrats!

Congrats! Awesome job!

Wow!!!

Unless you have a really good reason, I'd skip the heavy lifting. You can get your volume in a safer way. You know how it goes, if you lift heavy it's not 'if' you get hurt, but 'when'.

That's good to know! Makes me feel better about being on it for a while.

That's fantastic news! I'm about two months in. Been losing around 3lbs weekly. But I gained a little this past week. I'm trying not to get discouraged. Is it normal to have ups and downs?

And like @AndyPanda said in another thread, these peptide companies are more likely to get in trouble if a disgruntled customer reports them to the authorities. It's like, DEA, FDA...they all have their own things going on. The DEA even threatened to shut down my local pharmacy over something...