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Splitting 6mg tirz is the lower-risk first step before stacking - 3mg every 3-4 days smooths the curve and often fixes the day 5 craving return without adding another compound. Adding reta at low dose alongside tirz is higher-input: both are GLP-1 pathway and the nausea tends to be additive...

Staying at 5mg with continued loss is the conservative approach - push to go up isn't always necessary if the rate is working. Changing doctors for dose flexibility is an option if it stalls.

15 lbs in 12 days is early rapid loss - usually the first two weeks come fast before the pace normalizes. The dysautonomia inflammation note is interesting; the GLP-1 anti-inflammatory mechanism gets discussed less than the weight piece but the research is there.

I had the same life as you, FiberFam. It is helping me too.

MJ is not a shortcut!

that calculator's right, your math was off. either way we need to know what syringe — are you using a 100U 1mL like in your screenshot?

I haven't had my labs done recently, but I'm hoping to see some improvements there too! I'm also noticing my face is less puffy, which is a nice bonus!

Thanks so much everyone for the encouragement!

Different experience — it's the fit ones giving me grief about 'drugs' and 'cheating.' everyone judges something. breast feeding, rescue pets, plastic bottles... the judgment never stops. makes my head spin.

Thanks everyone!

Stopped for two months, thought I'd be fine. Nope—15 lbs back and cravings hit hard. When I restarted the same dose it didn't work the same way, had to go higher. Took three months to get back where I was. Added something else recently, hoping that helps long-term, but cold turkey never again.

It's been almost 14 weeks since I started the shots. This morning... I broke through a barrier! I haven't been under 200 lbs in probably 2 decades! Started at 235. Current is 199. Goal is 135. I'm over the moon! I wish I'd done this years ago!

I'm 71, gym rat, scientist, yoga teacher. Alternate Tesa 2mg fasting mornings with 200mcg Ipamorelin plus 200mcg CJC-1295 NODAC fasted before bed, one day off weekly. More conservative than daily Tesa, fewer sides, cheaper. Mechanically, 3 days at 2mg beats 6 days at 1mg. The ipamorelin combo...

I'm hoping I get the mental benefits some of you are talking about. Right now it's just blah. I know some people have amazing experiences. I saw someone on the reddits say, "My mental health has improved significantly. My overall mood is unlike any time I can remember." I NEED that!

No prob. Just wanted to make sure you were getting a dose that actually worked 😂

Uh, 2mg of NAD?

I'm down maybe 8-10 pounds the last 6 weeks, so yeah pretty early. I'll ask my doc about Reta, thanks!

So, I'm taking Tirz, and it's really helping with the cravings and quieting down the constant thoughts about food. But I've noticed I don't really enjoy doing my hobbies lately. It's like my brain is just 'meh' about everything. Is anyone else dealing with a lack of pleasure on this stuff? Any...

As a nurse, I totally see why prefilled pens are needed. MG and ML get mixed up all the time. MG is the amount of drug in the solution, and ML is the amount of solution. The biggest worry is the slowed digestion. They increase the dose gradually for a reason. Your GI tract can literally get...

I find myself wasting so much money on food that's going uneaten! It ends up spoiling before I get to it 😭😭😭