Recent content by Green-FWIW

Appreciate that. To me MJ is just one piece of the puzzle, not the whole solution. If I hadn't committed to overhauling how I eat, I wouldn't be anywhere near where I am now even with the medication helping. My diet shifts have been toward lower sodium, lower fat, lower carb, and lean protein. I...

Gradually transitioned to reta once I stalled out on tirz. First month ran 0.5mg weekly, then bumped to 1.0mg weekly just to gauge tolerance. Been going great. After that opening month, I really started pushing the reta dose up toward something therapeutic. My plateau finally broke somewhere...

The under-300 milestone deserves its own celebration - it carries disproportionate psychological weight compared to other intervals. Welcome to the club.

7.5mg barely eating and then stepping back to 5mg maintaining is the pattern where the dose creates more side effects than benefit and the lower dose is actually more sustainable. The OP stalled at max for over a year is a different problem from your 7.5 experience - they're stable at a dose...

Also down 70 and working on toning up is the parallel track the OP is probably thinking about. The maintenance and the muscle side tend to go together - the medication keeps appetite managed while the resistance work protects what you have. What's the current approach on the toning side?

Appetite suppression from day one is a great early signal - a lot of people don't notice anything until week 2 or 3. The nausea in week 1 settling down is the typical pattern. What dose are you starting at?

4 lbs at 10 weeks with active recomposition from protein and weight training is a different kind of progress than the OP's pound-a-week trajectory. The scale number at that stage often doesn't reflect the actual body change. Consistent pound-a-week for 7.5 months is the result of the OP not...

Not losing until 10mg on Zepbound is a real pattern - some people need the higher doses before the appetite suppression kicks in meaningfully. If the OP's doc is suggesting going back down after results, the question is whether maintenance or continued loss is the goal. What dose did you top out...

the PT-141 approved status creates an interesting regulatory asymmetry with MT-2 - the approved compound has a defined clinical profile while the unapproved one that produces similar effects through the same receptor occupies a different legal space. the mechanism overlaps at the receptor level...

The knowledge base here keeps building. First-hand reports from early starters are exactly what newer people need.

Maintaining through travel is a real result. A 10mg vial at slow escalation stretches further than most expect once you find your therapeutic dose.

The bidirectional libido effect on Reta is documented here. Some see a decrease, others - particularly those with PCOS or prior hormonal suppression - report a notable increase. The pathway runs through the same hypothalamic axis as appetite, which explains the individual variation.

Cagri hits a different receptor (amylin) than GLP1s, could be worth a look. Mots-c and Tesamorelin also have weight loss rep, though Tesa mainly targets belly fat.

i plan meals protein first. chicken breast thighs ground beef salmon pork. work out a lot so always a carb potato sweet potato rice pasta. then veggies. chili stir fry soups burritos stuff like that usually.

on sema from hers since nov 2024. started 195, lost 40 lbs by january, been flat or creeping up since. reduced appetite's gone. might be the pharmacy switch or coincidence but it sucks. on max dose they allow.