IGF-1 running to 400+ is above the fat-loss sweet spot for most - the 200-300 range is where people report the cleaner body comp shift with less glycemic disruption on top of Reta.
I hear you HormoneHustle, but honestly, I'm way more worried about the risks of being overweight. I'd likely have had a heart attack by now if I hadn't lost the weight. My doctor runs regular blood work so I feel pretty good about it.
I'm on 15mg and have been on MJ for 2.5 years. You usually stop losing weight after about 18 months; it's just maintenance from then on. I still deal with constipation that I've had for 2.5 years, but it's manageable. MJ keeps my weight loss of 229 lbs and A1C at normal levels.
Well, I just did my fourth injection at the lowest dose, and the noise is still there, but lighter. I think part of the thinking about food is just the need to actually plan and think about what to eat. My feeling of fullness comes and goes. I often feel like I *could* eat more, but I'm forcing...
It's definitely a risk we take. That is why vendor research is key. I look at reviews, other forums, and how consistent their testing is. I don't go with anyone who only tests once in a while or uses user screenshots as proof. We all know these are labeled 'research only' so we accept the risks...
I saw someone else's story... They were using Mounjaro and got pregnant. They had PCOS and other issues, and didn't think it would happen. They are now 5 months along!