When did you *feel* the Tirz?

StallStopper

StallStopper

Well-known member
Morning, all. I know this has been talked about, but I couldn't find a thread. I injected my second 2.5mg Tirzepatide dose last Friday, and I'm not feeling anything different. Google gives me all sorts of answers. I used semaglutide before and noticed reduced appetite and smaller portions within days of my first dose. I'm not experiencing that with Tirzepatide. Should I just wait, go up in dose, or what? Maybe I'm thinking too much but I value the experiences posted here.
 
I was told to begin at 5mg early on, and I felt it fast. Appetite vanished. Cravings gone. I lost about 8 pounds in the first week. I can't suggest you titrate faster than your protocol says. But hang in there!
 
It's different for everyone. I felt something within days of 1.5 mg. Maybe it was placebo. I've wanted to stop fixating on food for years. So, maybe the psychological effect was strong. Three months later, it is still working, but it may have started in my head.
 
It's totally individual. I noticed appetite changes maybe 8 hours later, but needing to increase over time is normal.
 
How long ago since you were on Ozempic and what was your dosage? Transferring from semaglutide to Tirzepatide often requires a higher starting dose. I felt appetite reduction and less food cravings within hours of my first dose.
 
I took my second dose Sunday, starting very low at 0.5 mg because I'm sensitive to medications. I worry it's not working (or won't). But at my low dose, I don't expect much until I increase. I notice less food noise. And I'm not having my afternoon slump. So something is going on!
 
It's been a while. I was on Ozempic in June/July (ended on 1MG) until insurance changed the coverage. I was thrilled to find this forum and the information here. I almost gave up on GLPs. It's possible my expectations were high, and I'm overthinking it, but it's nice to hear from others.
 
StallStopper said:
It's been a while. I was on Ozempic in June/July (ended on 1MG) until insurance changed the coverage.
Click to expand...

Semaglutide and Tirzepatide work differently. Give 2.5 mg time; "feelz" aren't the best measure. If no loss after a couple weeks, increase. You don't need to jump to 5.0; increments of 0.5 or 1.0 work.
 
It is probably because you took Ozempic. What was the last dose you got? I moved from Mounjaro 5 mg weekly to Reta 2 mg weekly. It took maybe 6 weeks and I felt nothing for 2 weeks, then tried pinning once every 5 days. Started to notice it and lost a couple pounds. Proceed slowly.
 
When I first tried sublingual semaglutide, I wasn't hungry. First time with sublingual trizepatide, I had to force myself to eat. Injectable Retatrutide made food unappealing. When I felt hunger, a third of the portion was enough, till the next day. Now, on injectable trizepatide, food sounds good, and I look forward to eating, but not like before GLP-1s. I just went to 5 mg after 6 months on injected trizepatide. I've been snacking and eating sweets recently, an odd turn after almost 10 months without much snacking. I'll see what happens.
 
For those of you using the pens, have you seen the cases designed to hold multiple pens in the fridge? I saw some cool 3D-printed ones that keep everything organized and fit better than the original boxes. Someone even suggested adding a spot for a Bluetooth temperature sensor, which is perfect for travel!
 
I saw someone on another forum say they lost almost 100 pounds and didn't change anything else. They said
Cut-Pizza said:
semaglutide has fixed what was wrong
Click to expand...
. I think that means for some people it's not about willpower... it's about hormones.
 
Second dose at 2.5mg and nothing yet is within normal range - the loading window is real, and most people don't feel the appetite shift until dose 3 or 4. The pre-workout mental hype running in parallel isn't wasted; the Tirz works on signaling, not on pushing past the resistance.
 
You must log in or register to reply here.
Back
Top