When did you *feel* the Tirz?

Hong Kong Yanpep International
The stomach response coming before appetite suppression is typical at 1mg. Hunger effect usually builds at 2-3mg. That Friday-to-Sunday lag is normal timing.
 
Afternoon drowsiness in the early Tirz phase is common. The energy pattern stabilizes as metabolism adjusts, usually within the first 2-3 months at dose.
 
Second dose is still loading - most people feel the Tirz effect at shot 3-4 rather than the first two.
 
Tirz onset is usually 2-4 weeks versus sema's faster first response - previous sema experience makes the slower start feel like it's not working.
 
8mg reta with 1mg sema for extra appetite suppression is a stack that works for some people when the reta alone starts to plateau. the skin sensitivity ceiling at 8mg is a common stopping point. for the OP asking about when tirz kicks in - the second dose is still really early. most people feel the full effect after the third or fourth.
 
How long before you actually felt something after your first shot? Took my first 2.5 dose yesterday, so it's been about 24 hours now, just waiting for the hunger or urge to eat to finally quiet down.
 
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