When did you *feel* the Tirz?

[FunkyBetter]

The stomach response coming before appetite suppression is typical at 1mg. Hunger effect usually builds at 2-3mg. That Friday-to-Sunday lag is normal timing.

 

[Riley_25]

Afternoon drowsiness in the early Tirz phase is common. The energy pattern stabilizes as metabolism adjusts, usually within the first 2-3 months at dose.

 

[Sweat_Go]

Second dose is still loading - most people feel the Tirz effect at shot 3-4 rather than the first two.

 

[Protein-Queen]

Tirz onset is usually 2-4 weeks versus sema's faster first response - previous sema experience makes the slower start feel like it's not working.

 

[Fit_Donut]

Tirz takes 2-3 weeks to kick in at 2.5mg - not the same timeline as sema.

 

[dozy_coasting]

8mg reta with 1mg sema for extra appetite suppression is a stack that works for some people when the reta alone starts to plateau. the skin sensitivity ceiling at 8mg is a common stopping point. for the OP asking about when tirz kicks in - the second dose is still really early. most people feel the full effect after the third or fourth.

 

[cinnamon_plateau]

How long before you actually felt something after your first shot? Took my first 2.5 dose yesterday, so it's been about 24 hours now, just waiting for the hunger or urge to eat to finally quiet down.

 

[pretzel_titrating17]

Actually felt my very first dose kick in. Sitting there a few minutes after taking it, I noticed something shift, almost like everything inside just settled. Hard to put into words honestly.

 

[Bobby2005]

Two weeks in for me now. Felt it working almost immediately, within about 12 hours actually. Know it varies person to person, but I'm clearly sensitive to it, dosing on schedule today basically guarantees I'll feel it by tomorrow.