Ozempic 1mg to 2mg: Jump or Split?

glow-up

Well-known member
Hi everyone,

I haven't had much luck with weight loss on Ozempic so far. I've been on 1mg for a year and a half, and I've only lost about 15 pounds. On the plus side, my A1C is great. It's at 5.1, which is a big improvement. (It was around 5.8 with just Metformin.)

My doctor is willing to up my dose to 2mg, but she wants me to decide how to do it, either by stepping up gradually or splitting the dose. She recommended using insulin syringes instead of counting clicks for either method.

I'm curious to know what others have done when increasing their dose from 1mg to 2mg. Specifically:

* Did you go straight from 1mg to 2mg?
* Did you split the dose, like 1mg twice a week?
* Did you gradually increase the dose?
* Did you combine gradual increase and split dosing?
* Is it easier to use insulin syringes instead of counting clicks?

I'm probably overthinking this, but I want to minimize any potential side effects!

Edit: I'm also a little worried that increasing my dose could cause low blood sugar, since my A1C is already good. (I'm also taking 1000mg of Metformin ER daily.) I probably should check my blood sugar more often.
 
I'd suggest stepping up to 1.5mg and splitting that dose for about a month. Then, split the 2mg dose for another month before trying 2mg all at once. I've found that splitting the dose helps minimize side effects and keeps the medication level more stable. Counting clicks works just fine; no need for syringes. The 2mg pen has 74 clicks total, so 37 clicks is 1mg, about 27 clicks for 0.75mg, and 18 for 0.50mg.
 
glow-up said:
I have been a slow to no responder. I've been at 1mg for over 18 months with little weight loss.

Seriously? After that long with barely any results and no major problems, just jump to 2mg already! Other meds have people going way up in their doses, so don't be scared.
 
Hey, I just went from 1mg to 2mg a couple weeks ago after being on 1mg for about a year. No problems or side effects at all.
 
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Thanks for the advice, everyone! I think I'll try stepping up slowly to 1.5mg and see how that goes. I appreciate all the input!
 
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