Reta hit me pretty hard right from 1mg too - almost uncomfortably strong appetite suppression in the first week. I had to actually remind myself to eat. Everyone responds differently though so not seeing the effect at 1mg doesn't mean it won't come at a higher dose.
Starting at 2.5mg and hitting 4mg without much suppression and then cagri switching things up is useful to hear. Reta alone at those doses not doing much is more common than the forums suggest. What did the hunger feel like differently once cagri came into the picture?
2mg to 3mg for 4 weeks with no movement and prior Tirz experience in the mix - prior Tirz can sometimes mean the receptor pathway needs longer to show up cleanly on Reta. What's appetite doing, any difference there even if the scale hasn't moved?
286 to 266 in 1.5 months before adding Reta and then 5.3 lbs and 2.5 lbs in the first two weeks on it is a strong early response. 4 weeks at a given dose is enough data to make a meaningful decision on whether to adjust. What did decision day land on?
On shot six now, four rounds at 2.5mg and two at 5mg, still haven't had a single side effect. Starting to wonder if something's off with me. Down about 4-5 kilos total over these six weeks, honestly a bit let down by that.