Reta sides at tiny dose?

Yeah, the side effects showing up before the actual appetite suppression effect is the typical Reta timeline. The first dose often just introduces the nausea and fatigue before the suppression piece catches up. Second dose or beyond is usually when you get a better read on whether it is working.

Zero side effects after 0.5mg and then titrating too fast after that is the pattern that gets people. The no appetite for 2 days at 0.5mg was probably the response - it just didn't continue because the body adjusted faster than the dose went up. Slower titration from a low start usually shows what it's actually doing.

The baseline supplement work before starting is worth doing - B vitamins and vitamin D at good levels removes those as variables if early side effects appear. The diet diversity point is also real; eating the same foods repeatedly tends to amplify intolerance responses that variety spreads out.

Tried the low dose route too and it just didn't agree with me. Grateful tirz works for me, and genuinely happy for the folks doing well on reta, just wasn't my match.