Coming off GLP-1 meds... anyone else?

Hong Kong Yanpep International
My annual wellness visit is coming up and she'll definitely order blood work. Besides the tests you mentioned, what else should I ask for? She didn't prescribe my GLP meds so I'm not sure whether to tell her I'm on Tirz.
 
packed everything except my shot for a trip. was supposed to do it today and again next thursday. never gone past a week except when i had surgery. what should i expect?
 
Almost a year on Wegovy, lost 60 pounds plus 20 before that. Getting compliments about 'melting away' but it's weird because I'm still 35 pounds from a healthy BMI and I never really had a problem with myself. Health-wise I have to lose weight but the mental side is harder. Anyone else struggling with this part?
 
6 months on ozempic, 3 at 1mg. nothing. no weight loss, no sides, gym 5x a week and clean diet. just stopped this week—paying out of pocket. unlucky i guess. but you're early, keep going.
 
Same here - stopped about 11 months ago, was at 2mg. Started at 199, got to 130, now sitting around 140-145 which honestly feels right given how much muscle I've added with strength training. I focus on how my clothes fit more than the scale number now.
 
Three years from .25 all the way up and then having it stop working is a hard journey. The switch to Mounjaro not adding much after that is useful to share here - it helps people understand that sometimes the mechanism change does not land the way you hoped. What ended up working for you after that?
 
The pre-GLP history with binge eating and restrictive approaches is really relevant context for how the medication feels different. GLP-1s reduce the urgency that drives bingeing rather than just cutting access - that's a mechanistically different intervention. For people who've been through the restrict-rebound cycle, having the neurological component addressed rather than just the behavioral one tends to stick differently.
 
Dealt with significant hair loss along with severe anxiety developing. That said, dropped a lot of weight too. Everyone responds differently to this medication class, but those two side effects specifically were enough to make me stop. Your experience may vary.
 
Thanks! Just came off it this past Friday. Might give it another shot down the road. Just glad the headaches are gone already and my stomach's feeling a lot better.
 
Quit taking it and about a month later felt terrible, all the inflammation came roaring back and the weight started creeping on again. Thrilled to be back on it now, don't think I'll ever stop again.
 
Definitely talk to your doctor about it. Something similar happened to me on ozempic, ended up quite ill and had to stop. Switched to mounjaro after that. Might be worth trying a break or a lower dose for a while.
 
That first medication was really hard here too. Been off it for half a year and the body still occasionally reacts to food like it's still active. Worked incredibly well though, both for blood sugar and weight. Now just working hard to manage without it.

Genuinely disappointing though. It was effective.
 
Reached my target weight (60M, 180 lbs) and stopped to test whether I could hold there on my own. Ended up climbing back to 195 in the months after, with glucose control slipping too (still on Metformin and Jardiance alongside it). While using Ozempic, regular meals only cause normal, brief spikes, but off it my numbers stayed elevated much longer. Restarted at 2.0 mg, back at goal weight now with no side effects. Planning to stay on it for good this time.
 
Feel that completely. Was doing fine with no issues until I hit 10mg. Then came two days of brutal diarrhea. Took a full month off to let my stomach settle before restarting at 5mg. Going okay so far. If it keeps happening on a regular basis, might be worth weighing whether it's really worth it. Maybe the ozempic pills, or stepping away from GLP1 entirely could be the answer. Missing work over this isn't an option for me, so a repeat episode means I'm done with it. Got a solid head start from this medication though, hoping I can keep the momentum going through diet alone if it comes to that. Good luck!
 
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