Coming off GLP-1s: Success!

Congrats! What an amazing achievement you've earned. You worked hard and deserve all the good coming your way. Keep going and hold the faith. Good luck staying successful.

Coming off with maintained results is the goal the medication is supposed to set up, not the exception - the people who transition off successfully are typically the ones where appetite recalibration and portion habits locked in during the treatment window.

What's your skincare routine? You look like you shed a decade, especially after coming off all this. My friend's going through perimenopause and would love to know. Big congratulations, that's an awesome success!

Went through this myself a few months back. Brought it up with my doctor and we jointly decided stopping made sense. Stuck with it four months, barely any weight came off, constant exhaustion, and I couldn't find joy in a single thing.

How long were you actually on it? And now that you've been off a while, how did that transition go? Did you also make major lifestyle changes like exercising more? Seeing solid results myself, but it's mostly from reduced appetite, and I'm worried the hunger comes roaring back the moment I stop.

Progress has stopped entirely. Now the goal's shifted to gaining a little back, or at least holding the line. Insurance won't approve stepping down to the smaller amount, so staying put at the current level but skipping alternate weeks. Considering tapering off completely. Type 2 diabetes stays fully controlled throughout. Started around 220, targeted 145, currently floating around 135 give or take a few pounds.

Same experience over here. Done wonders for bloodwork but the scale hasn't really moved. Lost a modest amount, mostly chalking that up to water weight and eating differently. Did pause it at one point since it didn't seem to be doing much, and during that break gained some back with cravings going through the roof. Decided to restart mainly to hold steady and keep the other health benefits going.

Nope, it didn't come roaring back. I was on it about 9 months, reached goal weight, then stopped. Losing the weight, getting my insulin sensitivity sorted and picking up better habits (I never realised how many calories were in food) reset everything, I think. Hunger does come, but normal hunger, and snacking isn't a thing for me now. 6 months later I'm still at my finishing weight.

Metabolic dysfunction is the core reason. When that's what made you heavy, or kept you there, a stretch on a GLP1 doesn't erase it, which is where the blood pressure and cholesterol comparisons come in. Plenty of people stop the drug, keep strictly to the eating and training plan they built on it, and still regain. You hear the same from people who kept a normal weight until pregnancy or perimenopause, then suddenly every trick that always worked stops holding the weight down. CICO alone no longer explains it. Calories in can still be logged, yet calories out have shifted somehow. Some big gains also come from temporary circumstances, without insulin resistance or any long-standing barrier to reaching a healthy weight. Groups likely differ in important ways.

Me. Sorta. Zepbound for me ran 5 months, March 2024 to August 2024, and I lost 60 pounds, about 254 to 190. Quitting cold turkey was my choice, since my husband and I wanted to try to conceive. That took a while and needed IVF. From August 2024 to April 2026 I lost another 30 pounds with trizep, reaching about 163. Hard? Yes. Did food noise return at full strength? Oh yeah. What helped was pure determination to stay well for a pregnancy, plus balance. Pasta is my favorite, twice a day if possible, so I balanced my meals across the week and chose wiser. It got easier over time but the first weeks off the shot were hard. We are pregnant now, so weight has crept back, which is fine. I do not know how postpartum will go, but if I cannot lose it, I would not mind Zepbound again.