Secretagogues before GH?

the peak-youth GH target is worth examining carefully - GH secretion at 21 represents peak physiology, not optimal adult function. targeting restoration to an age-appropriate level rather than a peak-youth reference tends to produce better outcomes with less side effect burden. pushing into higher dosage territory for secretagogues does not always produce proportionally better results and adds more to the side effect profile

I don't think you're following what I'm saying. Growth-hormone-releasing compounds trigger release of the hormone itself, that's literally why nearly everyone using them measures effectiveness by how much hormone actually gets released.

That study looked at effects from directly administering the hormone repeatedly, rather than effects from repeated hormone release triggered by compounds that stimulate release. That's exactly why I said the study applies here, the comparison is completely valid if your goal is examining hormone effects.

However, if your reason for taking these releasing compounds isn't actually about the hormone effect itself, and instead you've got some other motivation, say hunger control for instance, then sure, your point would hold up. Otherwise it just doesn't track logically.

Believe whatever you want though, that's your call.

Bro, gh, hgh, rhgh, somatropin, whatever, it's all chemically identical, hgh-191aa. Nothing you stack with a secretagogue will ever beat gh itself, because all a secretagogue does is prompt your body to let go of a portion of the gh already sitting in it. Injected gh skips those limits, so whatever your pituitary can make or release doesn't matter, you can always just take more. Nothing new here, bodybuilders had this figured out ages back. The ghrp/ghrh peptides have been known to medicine for ages, and the bodybuilding crowd since the 80s figured out that gh melts more fat than they ever will since there's no ceiling on how much gh you can have.

I have no argument with the HGH guys, but the body is built for pulsatile GH release rather than constant exposure, if you care about health. Look into how natural GH pulses, along with the way organs react. (Muscle obviously grows fast when flooded with endogenous GH, no disagreement there.) At 71 ive had excellent results using gh secretagogues. Nightly Sunday through Thursday I take Ipamorelin with CJC-1295 (no DAC) at bedtime, and morning tesamorelin goes in Tuesday, Thursday and Saturday. My IGF-1 is nearly double the age-matched norm, comparable to a mid-40s average, so trimming some secretagogues might be needed.