Crazy appetite suppression?!

Bridging from Tirz to Reta and expecting to come back to Tirz is actually a useful long-term framing. The combination of Tirz and Reta for the suppression in the OP makes sense especially if they found either one alone not quite doing everything. What dose are you at on each right now?

Spent three months on tirz at 10mg and started gradually swapping it for reta, climbing gradually in one-milligram steps. Because everyone says it's the better option, right?
By week two the food chatter and hunger had roared back with a vengeance. Pushed through anyway, but by week four (6mg tirz plus 4mg reta) I finally reversed course. With tirz back at the 10mg level, hunger and the mental chatter around food have mostly settled down again. Sticking with tirz for the foreseeable future since dropping weight is what matters most to me here.

You mentioned no appetite suppression, does fullness still hit faster once you actually start eating? Reta barely dulls my hunger at all honestly, which I actually see as a plus, but once food's in front of me I fill up much quicker than before. My wife ran tirz and switched to reta for maintenance. According to her, tirz crushed her appetite way harder, but on reta she can eat more freely and her weight's held rock steady anyway.

Have you tried tirz at all? Could suit you better than reta if stronger appetite control is what you're after, rather than piling on another compound.

Been running Reta and Tirz together, both at fairly low doses, somewhere between .5 and 1.5mg. Might be because the dose was low that I couldn't tell which one was doing more on the appetite front, but between the two of them it definitely gets suppressed.

I'll test spacing shots 3 to 4 days apart to see if the side effects drop. What's the smallest tirzepatide dose that you found still holds your appetite down?

Tried that too. For me reta lacks the appetite-killing effect that tirz has. I put weight on it, so I went back. Have you tried adding it yet? Curious how it goes for you.

Monday and Friday I do 3 mg tirz, then 3 mg reta on Wednesday, and that hits me way harder than 10 or 12 mg of tirz on its own. Food noise is where it shows most. Appetite and cravings stay far more under control on the combo than on big-dose tirz alone. Reta by itself is rough for me, with anhedonia and a weird dopamine feeling, and it barely touches my food noise solo. So for me the pairing is the secret sauce. Neither one alone gets there.

She says it's not really moving the scale for her and the hunger cutting part barely registers either. We're 40 weeks into reta at this point. Same deal for me honestly, no real suppression, but I just don't eat much to begin with since I'm holding at a dose meant for upkeep. Could always push the dose higher, no real issue there, and I've seen people here get good results tacking tirz on top. Cagri's sitting available too if I ever want to try stacking that instead.

honestly the appetite thing isnt really what im after right now, im way more focused on the weight loss itself. once i hit maintenance i think im going to switch back over to tirzepatide.

Same thing happened to me. Started July 2023, lost weight right away with zero side effects, total super responder, around 75 pounds down total. Topped out at 2.5mg before easing off, landed near 1mg equivalent, enough to keep food thoughts quiet. Come December I missed my usual Sunday dose, figured I'd resume next week. That turned into six weeks of skipping. Appetite roared back so I restarted, but my body stopped caring entirely. Went up gradually watching for side effects, felt nothing the whole climb, way past where I used to feel it. Nothing else gave me that mental freedom from obsessive counting. ADHD plus three kids means pure impulse eating for me. Changed everything while it worked. Thinking tirzepatide's next.