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5mg with zero cravings even if volume control is loose is a really useful distinction. The craving piece going away makes intake management so much more doable even when portion size isn't fully handled. What dose did you start at to get to 5mg?

the goal-first approach to peptide selection is the right order of operations - knowing what outcome you are trying to produce determines which compounds are relevant and at what dose, while starting with a list of compounds and working backwards to justify them produces a protocol with no clear...

PCOS plus GD history makes Mounjaro the cleaner fit over sema.

Slow loss rate is also better for lean mass preservation - the body has time to adapt and hold muscle during a gradual deficit.

The 7.5mg plateau followed by gain is the signal that the dose is no longer adequate rather than a lifestyle issue - GLP-1 receptor response at that dose level was the bottleneck. Moving to 10mg and recovering weight confirms the biology, not the protocol.

stopped working doesn't mean plateau and regain though. i don't see evidence of real weight comeback once dose is maintained. it hits a set point and holds there. the set point seems dose-dependent, and low-and-slow doesn't match the trial data on upper limits.

I get what you mean. I've realized a lot of what I thought I wanted, I don't actually enjoy doing anymore in the same way. Vacations used to be all about eating constantly and now... I just don't crave that. My whole outlook on food has shifted. I'm not strict about rules but also don't feel...

fda should approve this for more conditions. never got coverage cause i'm insulin resistant, not diabetic, and it's only covered for diabetes. way more people need it for ir, pcos, weight loss but insurance won't cover. this barely changes anything.

Started at 177 (I'm 5'1 so really short) down to 145 in 9 months, about 18% of my weight. Clothes fit like they did before my mid-40s. Only ever used 0.25mg Wegovy, tracked heavy, worked out. Want to ask my doc to hold the dose and just maintain around 145.

Mounjaro at 12.5 for about a year now, stuck around 290 (down from 410). Just started Vyvanse for ADHD and heard it can help with weight. Once I'm stabilized on it, think it might push past this plateau? Any experiences?

I've been on Mounjaro 7.5mg for 6 months and noticed way more hair shedding lately. It feels thinner too. Has anyone dealt with this? Any supplements or tips that actually help? Looking for real answers here.

These aren't addictive in the traditional sense, but rapid weight loss can hit hard with nausea, fatigue, appetite loss—especially stacked with depression and isolation. Might be worth asking docs to look at the whole picture, not just one med.

Bipolar here too. Felt some of the same stuff, especially the compulsive side. Treated bipolar with some control before, but this med really helped pull the compulsion back.

i've got a few autoimmune disorders and these meds are helping all of them by cutting down inflammation. it's been a game changer for me.

That's awesome! How are you feeling? How many calories a day and are you taking supplements? Definitely talk to your doc about a healthy stopping point tho.

I always make sure to get extra needles when I pick up my pen. There's always a little bit left over, and I hate wasting it. This is exactly what I do!

I've never thrown mine out. I use every last bit. I change the needle each time and keep it capped in between uses.

Nope, keep using it as long as it doesn't look cloudy to you!

If you're using the green 1mg pen, you can still do smaller doses. You just have to count the clicks. 37 clicks is half a mg.

There's a calculator at fatscientist.com that does all this math for anyone who doesn't want to.