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The day 4-5 hunger return at the starter dose is consistent - the suppression window with 2.5mg is narrower, and the gap shows up around where yours did. Getting full faster is the signal that holds. Food noise at day 4-5 tends to moderate as the dose escalates. Nine doses in with it returning...

The impulse to save the best bite is one of the more surprising behavioral shifts - the reward anticipation that used to drive eating gets recalibrated so the peak of the meal loses its pull. Eating in order of nutrition rather than pleasure is a downstream effect of the appetite circuit...

A clean switch rather than combination is usually recommended at plateau - adding Reta to stalled Tirz adds receptor coverage but also adds cost and management complexity. Starting Reta at a low dose (2-4mg) after a brief Tirz washout is the standard protocol. Muscle protection applies...

Almost everything you said matches me — high-pressure job, young kid, late-night eating. I also took my first shot Friday. Never realized I had food noise til the dose hit. Cravings gone, one small piece and I'm done. By day 5 it's creeping back though.

started scared of throwing up. happened once after drinking. body signals when to stop eating and drinking—listen to that and you're mostly fine. when it did happen, way milder than i remembered. just mild discomfort then over. not the long nausea hell.

peptides degrade over time no matter what, but refrig at 5c keeps it minimal if you're using within a year. larger molecules like gh and its derivatives—freeze those. glp1's are complex and actually pretty stable.

still figuring out maintenance for me. keeping the dose really low at 0.3mg and pinning every 10-14 days. a friend's held her goal weight like this for 6+ months and i've been solid for 2 so far.

OMG that's kinda gross, no offense. I can't even imagine. People are wild.

It probably got dropped during shipping anyway... those delivery people are so overworked these days.

If the vial still has a vacuum, that's a good sign. But it's not a guarantee, they can be sealed even without a strong vacuum.

I love a good overfill, but I don't want to pay for it. I saw some R60 that tested at 75mg and they wanted more money for it as R75.

I hate when they advertise the overfill. Like, "Tirz 28!" It's still tirz 25, ya cheapskate. I won't buy from anyone who does that. Especially if they use shady testing places.

Yep! I'm finding clothes I haven't worn in ages, and suddenly they're too big. Like, whoa! This dress used to be SNUG. Now it's hanging off me!

Totally agree!

Flying next week, first time since losing 90+ pounds. Super stoked to not need an extender or worry about encroaching on the next person's seat! Congrats!

Do you need a script for the name brand or the knockoff? I'd like to trim down some fluff, but I don't have diabetes.

If generics actually become available there, I bet there will be a lot more people flying to Canada. 😄

That's wild about the shoe size changing. I didn't even know that was possible!

This is an awesome achievement! You go!

Thanks for posting, Wes19! Just a friendly reminder of the rules: No discussing unapproved semaglutide versions, and no buying/selling meds here. Don't answer suspicious DMs offering meds. Newbies, check out the for helpful info!