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The face transformation tends to be the most noticed by other people. The structure that was there all along becomes visible.

MOTS-C and SS-31 address different parts of the same mitochondrial pathway. If MOTS-C is clearly working, adding SS-31 is a logical step. Most report clearer energy improvement from the combination than either alone.

Inverted vial before pulling eliminates most pressure issues. The buildup usually comes from injecting air in first - skipping that fixes it.

Total newbie here, sorry if this is dumb. Based on Tirz's half-life, do you pin every 5 or 7 days? Does it matter after it builds up? What's your experience with that?

Without it, I'd be back to low-carb, high-protein, calorie deficit grind — but food noise and cravings would roar back. I don't lean on GLP-1s any harder than I lean on my BP meds. My body doesn't handle carbs right. This is the fix.

I'm wondering this too. Wife and i are at 2mg each. We order the 30mg vials so I am worried about storing. We might get to 3 or 4 mg soon. Is the freezer best for long-term storage?

After watching Janoshik talk about this on YouTube and reading some threads here, I'm going with a 10-week max, using 10mg vials. I'm OK with a slightly degraded dose by the end. Gotta practice good sterile technique, and I think the odds are low for issues in that time frame. As my dose goes...

So, what's the move with Retatrutide? Buying single vials as you go, or getting a stash? I just grabbed a 30mg vial, and I'm seeing mixed stuff about how long it's good for in the fridge. Plus, how long does the powder last if it's not mixed?

Over a year on sema now, down from 197 to 161. Had to cut everything—alcohol, sugar, dairy, gluten. I'm basically one meal a day and it sticks. Spinal injuries keep me sedentary but it works. Water and staying full longer makes the difference.

Really common on GLPs. The appetite suppression also mutes thirst, so you stop feeling like you need water. Keeps a bottle visible on your desk instead of the kitchen. Have a glass right after your shot as a habit anchor. Eat water-dense foods like cucumber and watermelon. Alarms don't work, but...

That's huge! Congrats!

Congrats!

Talk to your doctor about increasing your dosage if you aren't seeing the results you want.

Great read! Thanks for sharing your story.

Thanks everyone! I think I will stick to my current rhythm, then.

You look incredible! How long did it take you to lose the weight?

It's probably just water retention. Salty foods can cause that. Or it could be inflammation. Weigh yourself a few times a week to track your progress. If you see similar numbers a few days apart, then worry. You also might need to increase your dose.

Since late autumn, I've managed to drop about 17 lbs, which is awesome! It's been about a pound each week. Honestly, I haven't been pushing myself super hard, just making better food decisions. I'm neurodivergent and struggle with eating issues, swinging between extremes. Given I've got a long...

I'm only a few days into my journey on .25mg of sema, I was worried it would stop me enjoying food. I still get to enjoy what I like, I just don't eat as much, which is great. I am hitting the gym every day.

You look great in both photos!